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Head-to-head · The Match Score

ShedRx vs RxSpan MD

Both scored on the same six-factor Match Score. ShedRx wins this matchup with a 86 to 85 edge — a photo finish.

Higher Match Score

ShedRx

#6 · Grade B+

People who want an oral or sublingual option rather than weekly injections.

Visit ShedRx
VS

RxSpan MD

#12 · Grade B

Patients who prioritize maximum formulary breadth and verification over the lowest price.

Visit RxSpan MD

Factor by factor

The six sub-scores behind each Match Score. The quiz reweights these to your priorities — one provider can pull ahead for you on the factors you care about.

Budget Fit
84
70
Speed to Start
84
88
Formulary Match
92
94
Support Level
86
86
Flexibility
88
86
Transparency
82
88

Price, coverage & formulary

DetailShedRxRxSpan MD
Semaglutide$199/mo$249/mo
Tirzepatide$299/mo$329/mo
CoverageNot disclosedAll 50 states
Brand-name accessCompounded onlyYes
Oral / sublingualYesYes
Match Score86 · B+85 · B
Winner: ShedRx

ShedRx edges out RxSpan MD, 86 to 85 on the default Match Score. A weight-focused program that also offers an oral/sublingual route for the needle-averse.

RxSpan MD is still a fair pick if its strengths line up with yours — best for: Patients who prioritize maximum formulary breadth and verification over the lowest price.

Worth a look either way: our overall #1 pick is CoreAge Rx (Match Score 91) — nationwide access, both molecules at one flat price, easy to cancel. Or take the 6-question quiz to see your personalized match.

Assume any provider we list may compensate us, at no cost to you. It never changes the Match Score.

Full ShedRx reviewFull RxSpan MD review

More head-to-heads

Or browse alternatives to ShedRx and all comparisons.

Pricing, states and verification reflect each provider's public disclosures at last review; the Match Score and its sub-scores are our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.