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Head-to-head · The Match Score

Enhance MD vs Onyx Weight Loss

Both scored on the same six-factor Match Score. Enhance MD wins this matchup with a 85 to 62 edge.

Higher Match Score

Enhance MD

#6 · Grade B

Patients who value clear tiered pricing and ongoing lab-backed provider care more than the lowest sticker price — and don't need brand or a pill.

Visit Enhance MD
VS

Onyx Weight Loss

#261 · Grade C

People who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl.

Visit Onyx Weight Loss

Factor by factor

The six sub-scores behind each Match Score. The quiz reweights these to your priorities — one provider can pull ahead for you on the factors you care about.

Budget Fit
80
43
Speed to Start
80
38
Formulary Match
84
72
Support Level
90
74
Flexibility
84
55
Transparency
92
90

Price, coverage & formulary

DetailEnhance MDOnyx Weight Loss
Semaglutide$212/mo$228/mo (starting dose, compounded)
Tirzepatide$280/mo$280/mo (starting dose, compounded)
Coverage39 states8 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjectable onlyInjectable only
Match Score85 · B62 · C
Winner: Enhance MD

Enhance MD edges out Onyx Weight Loss, 85 to 62 on the default Match Score. A transparent, tiered compounded program with dose-flat pricing, built-in lab testing every six months, and NAD+ care alongside your GLP-1.

Onyx Weight Loss is still a fair pick if its strengths line up with yours — best for: People who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl.

Worth a look either way: our overall #1 pick is CoreAge Rx (Match Score 91) — nationwide access, both molecules at one flat price, easy to cancel. Or take the 6-question quiz to see your personalized match.

Assume any provider we list may compensate us, at no cost to you. It never changes the Match Score.

Full Enhance MD reviewFull Onyx Weight Loss review

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Pricing, states and verification reflect each provider's public disclosures at last review; the Match Score and its sub-scores are our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.