MatchScript · Guides · Updated July 2026
The complete GLP-1 guide library.
Everything we know about getting weight-loss medication right — choosing a provider, what it costs, which molecule fits, and how to use it safely. Every guide is sourced to primary research or official labeling.
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All 32 ranked →We may earn a commission if you start care through some of these links, at no extra cost to you. What we write about a provider is the same either way, and every Match Score is computed from the six published factor sub-scores. See our disclosure.
- 191CoreAge RxVisit
- $149/mo
- All 50 states
- A− match
- 287EdenVisit
- $239/mo
- All 50 states
- B+ match
- 386HealthRXVisit
- $189/mo
- All 50 states
- B+ match
- 486ShedRxVisit
- $199/mo
- All 50 states
- B+ match
- 586Gala HealthVisit
- Not disclosed
- All 50 states
- B+ match
Not sure which line is you? Six questions reweight these same sub-scores to your priorities and re-rank the list.
Take the match quizChoosing a provider
How to pick a telehealth GLP-1 program you can trust — and stick with.
How to Choose a GLP-1 Provider That Fits You
A friendly checklist for picking a GLP-1 telehealth provider — budget, formulary, speed, support and coverage — plus how our quiz matches you.
Read the guideBest GLP-1 Provider by Need: Budget, Oral, Fast Start, or Nationwide
The best GLP-1 provider depends on your need. Our picks for budget, oral options, fast starts, and nationwide access — matched to what you want.
Read the guideBest GLP-1 Provider for Long-Term Use: What Maintenance Evidence Says
GLP-1s work as long as you stay on them. Here's what the maintenance trials show, and how to pick a provider you won't outgrow in year two.
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Cost & coverage
What GLP-1s really cost without insurance, and whether your plan will pay.
How Much Does Semaglutide Cost Without Insurance? (2026 Telehealth Pricing)
Brand Wegovy cash price vs. compounded telehealth pricing, what's included, plan-length discounts, and HSA/FSA — real 2026 semaglutide pricing.
Read the guideHow Much Does Tirzepatide Cost Without Insurance? (2026 Telehealth Pricing)
Brand Zepbound self-pay price vs. compounded tirzepatide telehealth pricing, what's included, and HSA/FSA — real 2026 tirzepatide costs without insurance.
Read the guideDoes Insurance Cover GLP-1 Weight-Loss Drugs? (2026 Coverage Reality)
The real state of GLP-1 coverage in 2026: commercial plans, Medicare's weight-loss exclusion, Medicaid, prior authorization, and why so many people pay cash.
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Compare the medications
Semaglutide vs. tirzepatide, injections vs. oral, and compounded vs. brand.
Semaglutide vs. Tirzepatide: Head-to-Head on Weight Loss, Side Effects, and Cost
Mechanism, the pivotal STEP and SURMOUNT trials, the head-to-head data, tolerability, and real telehealth pricing — an honest semaglutide vs tirzepatide guide.
Read the guideInjections vs Oral or Sublingual GLP-1: Which to Pick
Injectable GLP-1s have the big trials behind them; oral and sublingual options trade some evidence for convenience. A measured guide to picking your format.
Read the guideCompounded vs. Brand-Name GLP-1s: What the Evidence Actually Shows
FDA approval status, the 503A/503B pharmacy split, the shortage resolution, safety, and cost — an honest, sourced look at compounded vs brand GLP-1s.
Read the guideIs Compounded GLP-1 Legit and Safe?
A measured look at compounded GLP-1: what 503A and 503B pharmacies are, how LegitScript and the FDA fit in, and how to vet a provider.
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Using the medication
Dosing, side effects, protecting muscle, and what happens when you stop.
GLP-1 Dosing & Titration Schedule: Semaglutide and Tirzepatide Step-Up Charts
The standard semaglutide (Wegovy) and tirzepatide (Zepbound) titration schedules, why the slow step-up matters, maintenance doses, and missed-dose guidance.
Read the guideGLP-1 Side Effects and How to Manage Them (Nausea, GI, and Red Flags)
What semaglutide and tirzepatide side effects feel like, when they hit, how to blunt nausea and GI upset, and the red-flag symptoms that need a clinician.
Read the guideDo GLP-1s Cause Muscle Loss? What the Evidence Says (and How to Protect Lean Mass)
GLP-1 weight loss includes some lean mass — here's what the trial data actually shows, why it happens, and how protein and resistance training protect muscle.
Read the guideWhat Happens When You Stop Taking a GLP-1? (Weight Regain & How to Come Off)
The evidence on weight regain after stopping semaglutide or tirzepatide, why it happens, and how to taper and build a maintenance plan that holds.
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Ready to find your match?
Read the guides, then let the quiz weigh budget, molecule, and support into an honest Match Score and surface the providers that fit you.