Onyx Weight Loss review
Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states.
- Scores never bought
- 537 providers tracked
- Every factor auditable
- Updated July 2026
Semaglutide here is $228/mo (starting dose, compounded) — $29 above our category median of $199.
- Semaglutide
- $228/mo (starting dose, compounded)
- Tirzepatide
- $280/mo (starting dose, compounded)
- Coverage
- 8 states
- Brand-name
- Compounded only
- Oral option
- Injectable only
- Verification
- Not independently listed
Best for: People who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl.
MatchScript's take: Our #292 pick of 537 — a focused, straightforward program.
The factor breakdown
Onyx Weight Loss on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Semaglutide from $228/mo (starting dose, compounded) puts Budget Fit at a below-par 43 — above the budget tiers.
Limited or undisclosed state coverage can slow your start, for a below-par 38 on Speed to Start.
Onyx Weight Loss sticks to compounded injectables, for a below-par 72 on Formulary Match.
Support lands at a below-par 74 — lighter, meds-first support.
Flexibility scores a below-par 55 — fewer levers to flex your plan.
Open pricing and coverage detail put Transparency at a strong 90.
Pricing in context
How Onyx Weight Loss's monthly price sits against the category median and the cheapest provider we track.
| Monthly price | Semaglutide | Tirzepatide |
|---|---|---|
| Onyx Weight Lossthis providerVisit | $228/mo (starting dose, compounded)+$29 vs median | $280/mo (starting dose, compounded)+$6 vs median |
| Category median430 tracked | $199/mo | $274/mo |
| Cheapest trackedMondaeVisit | $87 per 28 days (13 charges a year) | $126 per 28 days (13 charges a year) |
What we like
- Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
- Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
- Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
- Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
- Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team
The caveats
- Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
- No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
- Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
- Labs not included or mentioned; no baseline bloodwork protocol published
- Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly
Who it's for — and who should skip it
Onyx Weight Loss is for people who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl.
Skip it if that doesn't sound like you. A closer fit may be SkinnyRx (Match Score 64) — or take the quiz to see where Onyx Weight Loss lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
Onyx Weight Loss against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | Onyx Weight Lossthis provider | CoreAge Rxour #1 | FORM (by GBY)closest scorer |
|---|---|---|---|
| Sema price | $228/mo (starting dose, compounded) | $99/mo at every dose | $299/mo compounded (no dose tiers) |
| Coverage | 8 states | All 50 states | 48 states plus D.C. (excludes Alaska and Mississippi) |
| Formulary | Injectable | Injectable | Injectable + oral + brand |
| Match Score | 62 · C | 91 · A− | 62 · C |
Onyx Weight Loss, answered
Is Onyx Weight Loss legit?
Onyx Weight Loss is a real, operating GLP-1 telehealth program. LegitScript certification is the third-party check worth asking for — look for the seal on their site and confirm your prescriber is US-licensed at intake. Like most programs here it dispenses compounded GLP-1s, which are made by a licensed pharmacy but aren't FDA-approved.
How much does Onyx Weight Loss cost?
Onyx Weight Loss lists compounded semaglutide from $228/mo (starting dose, compounded) and tirzepatide from $280/mo (starting dose, compounded) — above our category median of $199/mo. These are the provider's public figures at our last review (July 2026); confirm on their site, since some teaser tiers step up after month one.
Does Onyx Weight Loss ship to my state?
Onyx Weight Loss operates in a limited set of states (8 states). If yours isn't on that list, you'll need a nationwide provider instead.
Onyx Weight Loss vs SkinnyRx — which should I pick?
They score within a few points of each other: Onyx Weight Loss at 62/100 and SkinnyRx at 64/100, so neither wins on the headline number. Onyx Weight Loss is the better fit for people who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl. SkinnyRx suits shoppers who want a tablet as well as an injection on either molecule, and who read the term attached to an advertised rate before they read the number. Run the quiz and the weighting shifts to whichever of those matters more to you.
Pricing & state data last verified July 2026 from Onyx Weight Loss's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Onyx Weight Loss's site. Not medical advice; see our disclosure.
Semaglutide here is $228/mo (starting dose, compounded) — $29 above our category median of $199. Tirzepatide is $280/mo (starting dose, compounded). It scores highest on what it is willing to publish up front. Best suited to people who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl. If that is not you, SkinnyRx is the closest thing to it here.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest Onyx Weight Loss here.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match84/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry in this ranking.84/100
- #3Match83/ 100EdenA polished, high-disclosure compounded program with strong nationwide coverage and hands-on support.83/100
- #4Match85/ 100RoA heavyweight telehealth brand with brand-name access and a polished experience — but opaque compounded pricing.85/100
- #5Match85/ 100No BS RXThe highest Transparency score here, and it is not close: twenty-four prices on one public page and four dispensing pharmacies named with street addresses.85/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| Silhouette MD#293 | 62 | $149/mo (compounded) | $299/mo (compounded) | Coverage not published | Alternatives | Visit |
| Spry#294 | 62 | $216/mo | $349/mo | Coverage not published | Alternatives | Visit |
| Sumbare Wellness#295 | 62 | $199/mo (all doses, compounded) | $199/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| TeleHealth Weight Solutions#296 | 62 | $325/mo (all doses, compounded) | $375/mo | Coverage not published | Alternatives | Visit |
| The Virtual NP#297 | 62 | Not disclosed | Not disclosed | 7 states | Alternatives | Visit |
| Tru2u#298 | 62 | $225/mo | $345/mo | Coverage not published | Alternatives | Visit |
| HealthOn#299 FDA issued Healthon Inc. dba Healthon a warning letter in September 2025. See FDA's warning-letter database. | 62 | $205/mo | $315/mo | Coverage not published | Alternatives | Visit |
| Livea#300 | 62 | $170/mo | $272/mo | 4 states | Alternatives | Visit |
| Luci#301 | 62 | $99/mo (starting dose, promotional rate, compounded) | $405/mo | Coverage not published | Alternatives | Visit |
| Invyncible#302 | 62 | $149/mo (0.45 mg dose, compounded with glycine + B12) | $180/mo (2.5 mg weekly, 4-week program, compounded) | 46 states plus DC | Alternatives | Visit |
| Trinity Meds#303 | 62 | $99/mo | $149/mo | Coverage not published | Alternatives | Visit |
| Valhalla Vitality#304 | 62 | $108/mo | $100/mo | Coverage not published | Alternatives | Visit |
| Superior Remedies#305 | 62 | $202/mo | $303/mo | 7 states — CA, IL, MI, NY, UT, VA, WI | Alternatives | Visit |
| Magnolia Regenerative Medicine#306 | 62 | $119/mo | $199/mo | 26 states | Alternatives | Visit |
| RENN Health#307 | 62 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Try Ageless#308 FDA issued Lovely Meds, Inc. dba Lovely Meds a warning letter in September 2025. See FDA's warning-letter database. | 59 | $279/mo (injection, month-to-month) | $349/mo (injection, month-to-month) | Coverage not published | Alternatives | Visit |
| LevelsRx#309 | 61 | $253/mo | $354/mo | Coverage not published | Alternatives | Visit |
| Livv#310 | 61 | $179/mo | $269/mo | Coverage not published | Alternatives | Visit |
| Clinic Secret#311 | 61 | $301/mo | $403/mo | Coverage not published | Alternatives | Visit |
| Heva Health#312 | 61 | $199/mo | Not disclosed | Coverage not published | Alternatives | Visit |
| InstaRX#313 | 61 | $252/mo | $353/mo | All 50 states | Alternatives | Visit |
| Tuyo Health#314 FDA issued Tuyo Health, Inc. dba Tuyo Health a warning letter in September 2025. See FDA's warning-letter database. | 61 | $155/mo | $349/mo | Coverage not published | Alternatives | Visit |
| MyStart Health#315 FDA issued Matthew Stern, CEO MyStart Health LLC. a warning letter in September 2025. See FDA's warning-letter database. | 61 | $303/mo | $303/mo | Coverage not published | Alternatives | Visit |
| Freya Meds#316 | 61 | $301/mo | $396/mo | Coverage not published | Alternatives | Visit |
Onyx Weight Loss is ranked on our best semaglutide providers, best tirzepatide providers and best GLP-1 programs boards, scored on the same six factors as every other provider there.