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Ranked #261 of 497 · Grade C

Onyx Weight Loss review

Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states.

Visit Onyx Weight Loss Or see your best match We may earn a commission if you start care through some of these links, at no extra cost to you. What we write about a provider is the same either way, and every Match Score is computed from the six published factor sub-scores. See our disclosure.

Onyx Weight Loss earns a Match Score of 62/100 (grade C) and sits #261 of 497 on our board under the balanced default weighting.

Semaglutide
$228/mo (starting dose, compounded)
Tirzepatide
$280/mo (starting dose, compounded)
Coverage
8 states
Brand-name
Compounded only
Oral option
Injectable only
Verification
Not independently listed

Best for: People who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl.

MatchScript's take: Our #261 pick of 497 — a focused, straightforward program, scored on the same six factors as everyone else.

The factor breakdown

Onyx Weight Loss on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.

Budget Fit43/100

Semaglutide from $228/mo (starting dose, compounded) puts Budget Fit at a below-par 43 — above the budget tiers.

Speed to Start38/100

Limited or undisclosed state coverage can slow your start, for a below-par 38 on Speed to Start.

Formulary Match72/100

Onyx Weight Loss sticks to compounded injectables, for a below-par 72 on Formulary Match.

Support Level74/100

Support lands at a below-par 74 — lighter, meds-first support.

Flexibility55/100

Flexibility scores a below-par 55 — fewer levers to flex your plan.

Transparency90/100

Disclosure here is thinner than the top of the board give a strong 90 on Transparency.

Pricing in context

How Onyx Weight Loss's monthly price sits against the category median and the cheapest provider we track.

Monthly priceSemaglutideTirzepatide
Onyx Weight Lossthis providerVisit $228/mo (starting dose, compounded)+$49 vs median$280/mo (starting dose, compounded)+$31 vs median
Category median353 tracked$179/mo$249/mo
Cheapest trackedTelos RxVisit $49/mo$99/mo

What we like

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

The caveats

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly

Who it's for — and who should skip it

Choose Onyx Weight Loss if people who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl.

Skip it if that doesn't sound like you. A closer fit may be Aquivia Health (Match Score 62) — or take the quiz to see where Onyx Weight Loss lands for your priorities.

See every alternative to Onyx Weight Loss.

How it compares to CoreAge Rx & the closest scorer

Onyx Weight Loss against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.

How it comparesOnyx Weight Lossthis providerCoreAge Rxour #1Aquivia Healthclosest scorer
Sema price$228/mo (starting dose, compounded)$149/mo$149/mo
Coverage8 statesAll 50 statesCoverage not published
FormularyInjectableInjectableInjectable + brand
Match Score62 · C91 · A−62 · C

Onyx Weight Loss, answered

Is Onyx Weight Loss legit?

Onyx Weight Loss is a real, operating GLP-1 telehealth program, but we don't find it on the LegitScript registry, so it carries less third-party verification than the certified providers on our board. It dispenses compounded medication, which isn't FDA-approved. Vet the prescriber and pharmacy before you commit.

How much does Onyx Weight Loss cost?

Onyx Weight Loss lists compounded semaglutide from $228/mo (starting dose, compounded) and tirzepatide from $280/mo (starting dose, compounded) — above our category median of $179/mo. These are the provider's public figures at our last review (July 2026); confirm on their site, since some teaser tiers step up after month one.

Does Onyx Weight Loss ship to my state?

Onyx Weight Loss operates in a limited set of states (8 states). If yours isn't on that list, you'll need a nationwide provider instead.

Onyx Weight Loss vs CoreAge Rx — which is better?

Both are on our board. Onyx Weight Loss scores 62/100; CoreAge Rx leads our default ranking at 91/100 for its flat nationwide pricing on both molecules and easy cancellation. Onyx Weight Loss can still win for you if its strengths match your priorities — best for: People who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl. Run the quiz to see which comes out ahead for you.

Pricing & state data last verified July 2026 from Onyx Weight Loss's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Onyx Weight Loss's site. Not medical advice; see our disclosure.

Verdict · Grade C · 62/100

Onyx Weight Loss earns a Match Score of 62/100 (grade C) and sits #261 of 497 on our board under the balanced default weighting. Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states. Best for: People who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl. If it isn't the right fit, Aquivia Health is a sensible alternative to weigh next.

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