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Head-to-head · The Match Score

ShedRx vs Direct Meds

Both scored on the same six-factor Match Score. ShedRx wins this matchup with a 86 to 82 edge.

Higher Match Score

ShedRx

#4 · Grade B+

People who want an oral or sublingual option rather than weekly injections.

Visit ShedRx
VS

Direct Meds

#20 · Grade B−

Patients who want to try a sublingual GLP-1 or keep both routes open, and can accept company-stated pricing that isn't independently confirmed.

Visit Direct Meds

Factor by factor

The six sub-scores behind each Match Score. The quiz reweights these to your priorities — one provider can pull ahead for you on the factors you care about.

Budget Fit
84
86
Speed to Start
84
78
Formulary Match
92
90
Support Level
86
78
Flexibility
88
88
Transparency
82
74

Price, coverage & formulary

DetailShedRxDirect Meds
Semaglutide$199/mo$179/mo
Tirzepatide$299/mo$224/mo
CoverageAll 50 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesYes
Match Score86 · B+82 · B−
Winner: ShedRx

ShedRx edges out Direct Meds, 86 to 82 on the default Match Score. A weight-focused program that also offers an oral/sublingual route for the needle-averse.

Direct Meds is still a fair pick if its strengths line up with yours — best for: Patients who want to try a sublingual GLP-1 or keep both routes open, and can accept company-stated pricing that isn't independently confirmed.

Worth a look either way: our overall #1 pick is CoreAge Rx (Match Score 91) — nationwide access, both molecules at one flat price, easy to cancel. Or take the 6-question quiz to see your personalized match.

Visit ShedRx Visit Direct Meds

Assume any provider we list may compensate us, at no cost to you. It never changes the Match Score.

Full ShedRx reviewFull Direct Meds review

More head-to-heads

Or browse alternatives to ShedRx and all comparisons.

Pricing, states and verification reflect each provider's public disclosures at last review; the Match Score and its sub-scores are our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.