Skip to content
MatchScript
Menu

Semaglutide or tirzepatide — which should I ask about?

They are different molecules: semaglutide targets one receptor (GLP-1) and tirzepatide targets two (GLP-1 and GIP). In head-to-head trial data tirzepatide has produced greater average weight loss, and it also costs more — a median of $273 a month here versus $199 for semaglutide. Which one is appropriate is a clinical decision for your prescriber, not a shopping choice.

Semaglutide vs tirzepatide →

Every figure is computed from the provider records behind MatchScript and dated. This is health information for education, not medical advice.

More answers

We may earn a commission if you start care through some of these links, at no extra cost to you. What we write about a provider is the same either way, providers we have a commercial relationship with are listed first on most boards, and every Match Score is computed from the six published factor sub-scores regardless. See our disclosure.