The best oral GLP-1 programs, matched to you.

1. #1

   Match84/ 100

   Strut Health

   Top match

   The only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry in this ranking.

   Regulatory notice

   FDA issued Strut Health, LLC dba Strut a warning letter in February 2026. You can read it in FDA's warning-letter database. We still list Strut Health, and we may earn a commission if you start care through the link on this page.

   Semaglutide:

   $131/mo

   States:

   49 states — list not disclosed

   Best for:

   People who want the strongest third-party pharmacy oversight available here, plus a needle-free lozenge option, without paying a premium for either.

   Visit Strut Health ↗Read the full review
2. #2

   Match82/ 100

   Telos Rx

   Cheapest verified

   The widest compounded menu in the ranking at a rock-bottom GLP-1 entry — microdosed semaglutide from ~$49/mo, tirzepatide from ~$99/mo, plus oral GLP-1, intranasal NAD+, recovery peptides and bioidentical HRT, all LegitScript-certified and HIPAA-compliant.

   Semaglutide:

   $99/mo injectable

   States:

   All 50 states

   Best for:

   Budget-first patients who want the cheapest GLP-1 entry alongside a broad wellness menu, and can accept an annual commitment and compounded-only, thinly-reviewed care.

   Visit Telos Rx ↗Read the full review
3. #3

   Match81/ 100

   HealthRX

   A LegitScript-certified, physician-supervised program with a rare oral GLP-1 tablet alongside injectables — both molecules, transparent no-insurance pricing, and a brand-name path.

   Semaglutide:

   $193/mo

   States:

   All 50 states

   Best for:

   Patients who want a verified, physician-supervised provider with an oral-tablet option and clear monthly pricing, and don't mind that some tiers are company-stated.

   Visit HealthRX ↗Read the full review
4. #4

   Match81/ 100

   ShedRx

   A weight-focused program that also offers an oral/sublingual route for the needle-averse.

   Semaglutide:

   $199/mo

   States:

   All 50 states

   Best for:

   People who want an oral or sublingual option rather than weekly injections.

   Visit ShedRx ↗Read the full review
5. #5

   Match81/ 100

   Sesame Care

   The one brand-name-only option here: you pick a named clinician at a posted price, and the medication is billed separately at cash-pay rates.

   Semaglutide:

   $149/mo brand Wegovy pill

   States:

   Not disclosed

   Best for:

   People who want FDA-approved Wegovy or Zepbound rather than a compounded version, and who would rather choose their clinician than be assigned one.

   Visit Sesame Care ↗Read the full review
6. #6

   Match80/ 100

   He & She MD

   He & She MD is a nationwide telehealth weight-loss clinic offering doctor-prescribed GLP-1 medications: compounded semaglutide and tirzepatide (injectable or oral), with brand-name…

   Semaglutide:

   $199/mo (monthly plan)

   States:

   All states except Louisiana (GLP-1)

   Best for:

   People who want a published GLP-1 price ladder, injectable or oral, and are willing to prepay a term to reach the low rate.

   Visit He & She MD ↗Read the full review
7. #7

   Match78/ 100

   Found

   A coaching-first program that now spans compounded injectables, an oral orforglipron option and brand-name Wegovy — priced low only if you prepay a year.

   Semaglutide:

   $289/mo month-to-month cash

   States:

   All 50 states

   Best for:

   People who want medication, membership and behavior-change coaching billed as one thing, and will commit to 12 months to get the advertised rate.

   Visit Found ↗Read the full review
8. #8

   Match78/ 100

   Care Bare Rx

   Weight-loss treatment from $199/mo across all 50 states plus Puerto Rico, spanning compounded injectables, oral tablets and brand-name Ozempic — but the price you actually pay appears only after intake.

   Semaglutide:

   $199/mo

   States:

   All 50 states

   Best for:

   People who want the widest set of routes on one account, including a brand-name path, and don't mind completing an intake before they see their real price.

   Visit Care Bare Rx ↗Read the full review

Oral GLP-1, answered

Which providers actually offer an oral GLP-1?

126 of the 528 providers we review sell a swallowed GLP-1 — a tablet, capsule or sublingual — as well as an injection, and publish a price. Strut Health leads here with a Match Score of 84/100. The best pick for you depends on your priorities — take the quiz to reweight the score.

Is an oral GLP-1 as effective as the injection?

Not dose for dose. Oral semaglutide is absorbed far less efficiently than an injection, which is why oral doses are numerically much larger, and Lilly's oral orforglipron showed lower mean weight loss at its labeled dose than injectable tirzepatide did at its. The honest trade is convenience against effect size, and it is a conversation to have with the prescriber rather than a decision to make off a ranking page.

Is a compounded oral GLP-1 the same as Rybelsus or Foundayo?

No. Rybelsus (oral semaglutide) and Foundayo (orforglipron) are FDA-approved brand products. A compounded oral is made to a prescription by a pharmacy and is not an FDA-approved finished product — a different thing, usually far cheaper, and worth understanding before you buy.

How does MatchScript rank these?

Every provider is scored on six measurable factors — Budget Fit, Speed to Start, Formulary Match, Support Level, Flexibility and Transparency. The Match Score itself is never adjusted for money: the number you see is the number we scored, and the calculation has no input for whether a provider pays us. Every score is printed next to every name so you can check that yourself. Ranking ORDER is a separate thing: providers we have a commercial relationship with are listed first, which is why a higher score can appear below a lower one. We may earn a commission from some links here, at no extra cost to you — see our disclosure and methodology.

Still deciding? Read whether compounded GLP-1 is legit and safe, compare it to the branded route in compounded vs brand-name GLP-1, or weigh the molecules in injections vs oral GLP-1, or weigh the molecules in semaglutide vs tirzepatide, or see the best semaglutide providers. You can also compare any two providers head-to-head or take the match quiz.

Rankings reflect MatchScript’s published methodology. This page is informational and not medical advice; compounded medications are not FDA-approved brand products. See our medical disclaimer.