Match81/ 100
Grade B−ShedRx
#10A weight-focused program that also offers an oral/sublingual route for the needle-averse.
- Sema
- $199/mo
- Tirz
- $303/mo
- Coverage
- All 50 states
Ranked by the Match Score
Alternatives to Optimized Health
Optimized Health scores 76 on our six-factor Match Score (ranked #51 of 528). Here are the providers we'd weigh against it, ranked by that same honest model. Or take the quiz for your personalized match.
Match79/ 100
Grade CFitish
#24A polished, nationwide program with an oral route and LegitScript certification — broad reach at a premium price.
- Sema
- $219/mo
- Tirz
- $339/mo
- Coverage
- All 50 states
Regulatory notice
FDA issued FITISH a warning letter in June 2026. You can read it in FDA's warning-letter database. We still list Fitish, and we may earn a commission if you start care through the link on this page.
Match91/ 100
Grade A−CoreAge Rx
#1#1 overallThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.
- Sema
- $99/mo at every dose
- Tirz
- $149/mo at every dose
- Coverage
- All 50 states
Match83/ 100
Grade BEden
#3A polished, high-disclosure compounded program with strong nationwide coverage and hands-on support.
- Sema
- $198/mo
- Tirz
- $298/mo
- Coverage
- All 50 states
Regulatory notice
FDA issued Eden Health International Inc. dba Eden a warning letter in June 2026. You can read it in FDA's warning-letter database. We still list Eden, and we may earn a commission if you start care through the link on this page.
Match77/ 100
Grade CHealthSource
#44HealthSource is a telehealth weight-management platform offering compounded semaglutide and tirzepatide (injectable and oral sublingual) dispensed through a US-based FDA 503A licensed partner pharmacy.
- Sema
- $199/mo (all doses, compounded)
- Tirz
- $299/mo (all doses, compounded)
- Coverage
- All 50 states
Match84/ 100
Grade BStrut Health
#2The only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry in this ranking.
- Sema
- $131/mo
- Tirz
- $151/mo
- Coverage
- 49 states — list not disclosed
Regulatory notice
FDA issued Strut Health, LLC dba Strut a warning letter in February 2026. You can read it in FDA's warning-letter database. We still list Strut Health, and we may earn a commission if you start care through the link on this page.
Match81/ 100
Grade B−HealthRX
#9A LegitScript-certified, physician-supervised program with a rare oral GLP-1 tablet alongside injectables — both molecules, transparent no-insurance pricing, and a brand-name path.
- Sema
- $193/mo
- Tirz
- $242/mo
- Coverage
- All 50 states
Match80/ 100
Grade B−yourEra
#13A personalized-health brand that lists its GLP-1 prices out loud — both molecules, plus NAD+ and microdosing, with an optional coaching-and-labs bundle, nationwide.
- Sema
- $199/mo
- Tirz
- $263/mo
- Coverage
- All 50 states
Not sure which fits you?
Answer six quick questions and we'll reweight the Match Score to your budget, format, timing, coverage and support — then rank every provider for you.
Take the quizPricing, states and verification reflect each provider's public disclosures at last review; the Match Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.