Defy Medical review
Defy Medical is a long-running telehealth clinic, best known for hormone replacement, that also prescribes GLP-1 medications for weight loss.
- Scores never bought
- 497 providers tracked
- Every factor auditable
- Updated July 2026
Defy Medical earns a Match Score of 52/100 (grade C) and sits #411 of 497 on our board under the balanced default weighting.
- Semaglutide
- Not disclosed
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Compounded only
- Oral option
- Yes
- Verification
- Not independently listed
Best for: Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups.
MatchScript's take: Our #411 pick of 497 — one of the few with a non-injection route, scored on the same six factors as everyone else.
The factor breakdown
Defy Medical on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Its lowest tier isn't clearly disclosed puts Budget Fit at a below-par 48 — above the budget tiers.
Limited or undisclosed state coverage can slow your start, for a below-par 58 on Speed to Start.
Defy Medical adds an oral/sublingual route on top of injectables, for a below-par 56 on Formulary Match.
Support lands at a middling 77 — lighter, meds-first support.
Flexibility scores a below-par 55 — fewer levers to flex your plan.
Disclosure here is thinner than the top of the board give a below-par 20 on Transparency.
Pricing in context
How Defy Medical's monthly price sits against the category median and the cheapest provider we track.
What we like
- Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
- Offers injection, ODT, and oral drop delivery forms
- Comprehensive blood testing and named medical director
- Established clinic with strong Trustpilot review volume
The caveats
- GLP-1 pricing not published on the website
- States served and shipping limits not disclosed
- Compounded versus brand status not stated online
- Lab-heavy, consult-first model may cost more upfront
Who it's for — and who should skip it
Choose Defy Medical if patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups.
Skip it if that doesn't sound like you. A closer fit may be Eclipse Medical Wellness (Match Score 52) — or take the quiz to see where Defy Medical lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
Defy Medical against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | Defy Medicalthis provider | CoreAge Rxour #1 | Eclipse Medical Wellnessclosest scorer |
|---|---|---|---|
| Sema price | Not disclosed | $149/mo | Not disclosed |
| Coverage | Coverage not published | All 50 states | 1 states |
| Formulary | Injectable + oral | Injectable | Injectable + brand |
| Match Score | 52 · C | 91 · A− | 52 · C |
Defy Medical, answered
Is Defy Medical legit?
Defy Medical is a real, operating GLP-1 telehealth program, but we don't find it on the LegitScript registry, so it carries less third-party verification than the certified providers on our board. It dispenses compounded medication, which isn't FDA-approved. Vet the prescriber and pharmacy before you commit.
How much does Defy Medical cost?
Defy Medical doesn't publish a clear compounded-semaglutide price up front. You'll typically see full pricing after the intake questionnaire. Get the all-in monthly number in writing before you pay.
Does Defy Medical ship to my state?
Defy Medical operates in a limited set of states (Coverage not published). If yours isn't on that list, you'll need a nationwide provider instead.
Defy Medical vs CoreAge Rx — which is better?
Both are on our board. Defy Medical scores 52/100; CoreAge Rx leads our default ranking at 91/100 for its flat nationwide pricing on both molecules and easy cancellation. Defy Medical can still win for you if its strengths match your priorities — best for: Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups. Run the quiz to see which comes out ahead for you.
Pricing & state data last verified June 2026 from Defy Medical's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Defy Medical's site. Not medical advice; see our disclosure.
Defy Medical earns a Match Score of 52/100 (grade C) and sits #411 of 497 on our board under the balanced default weighting. Defy Medical is a long-running telehealth clinic, best known for hormone replacement, that also prescribes GLP-1 medications for weight loss. Best for: Patients wanting GLP-1 in injection, ODT, or drop forms with thorough lab workups. If it isn't the right fit, Eclipse Medical Wellness is a sensible alternative to weigh next.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest Defy Medical on the board.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match88/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry on this board.88/100
- #3Match86/ 100HealthRXA LegitScript-certified, physician-supervised program with a rare oral GLP-1 tablet alongside injectables — both molecules, transparent no-insurance pricing, and a brand-name path.86/100
- #4Match86/ 100ShedRxA weight-focused program that also offers an oral/sublingual route for the needle-averse.86/100
- #5Match88/ 100Ondra HealthNear rock-bottom pricing on both molecules plus some brand access — a rare budget-and-breadth combo, nationwide.88/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| Eclipse Medical Wellness#412 | 52 | Not disclosed | Not disclosed | 1 states | Alternatives | Visit |
| EmbraceRX#413 | 52 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Gatlan#414 | 52 | Not disclosed | Not disclosed | 44 states | Alternatives | Visit |
| Hormonally Balanced#415 | 52 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Immortals#416 | 52 | $167/mo (microdose tier, compounded) | $180/mo (microdose tier, compounded) | Coverage not published | Alternatives | Visit |
| LaSara Medical Group#417 | 52 | $289/mo (compounded) | $399/mo (bundle, compounded) | Coverage not published | Alternatives | Visit |
| Maven Clinic#418 | 52 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Omnia TeleHealth#419 | 52 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Remedy Meds#420 | 52 | $299/mo (starting dose, compounded) | $399/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Stealth Health#421 | 52 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| T2D.com#422 | 52 | $999/mo (starting dose, compounded) | $999/mo (starting dose, compounded) | 1 states | Alternatives | Visit |
| TeleDocs360#423 | 52 | $399/mo (compounded) | $399/mo (compounded) | Coverage not published | Alternatives | Visit |
| Always Wellness and Recovery#424 | 51 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Better MedSpa#425 | 51 | Not disclosed | Not disclosed | 1 states | Alternatives | Visit |
| EverFit Medical#426 | 51 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Marek Health#427 | 51 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| MEDVidi#428 | 51 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Näky#429 | 51 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Omada Health#430 | 51 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Rixa Health#431 | 51 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Teladoc Health#432 | 51 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Transcarent#433 | 51 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Actin#434 | 50 | $169/mo (compounded) | Not disclosed | Coverage not published | Alternatives | Visit |
| Ambiante Health & Wellness#435 | 50 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |