System Labs review
A performance-and-longevity clinic that also prescribes a compounded GLP-1/GIP, priced openly at $179/mo once the first-month promo lapses.
- Scores never bought
- 537 providers tracked
- Every factor auditable
- Updated February 2026
System Labs is a performance-and-longevity clinic first: the catalog is built around NAD+, glutathione, sermorelin and MIC-B12, and the GLP-1 is one lander inside it.
- Semaglutide
- Not offered
- Tirzepatide
- $179/mo standing
- Coverage
- Not disclosed
- Brand-name
- Compounded only
- Oral option
- Injectable only
- Verification
- LegitScript-certified
Best for: People already drawn to a longevity clinic's wider peptide menu who want a dual-agonist GLP-1 alongside it, and who will read past the first-month price.
MatchScript's take: A longevity clinic with a GLP-1 sideline — and a $99 that is only ever the first month.
The factor breakdown
System Labs on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Scored on the $179/mo standing rate, not the $99 first month. A one-month promo is not a price, and letting it set the score would have put System Labs above providers whose low rate actually lasts.
Limited or undisclosed state coverage can slow your start, for a middling 78 on Speed to Start.
One GLP-1/GIP product and no semaglutide SKU at any price, no oral route and no brand lane gives a below-par 66 — GLP-1 is a sideline to a longevity catalog here.
Support lands at a middling 78 — lighter, meds-first support.
Flexibility scores a middling 78 — fewer levers to flex your plan.
LegitScript certification helps, but thin pricing and sourcing detail keeps Transparency at a middling 76.
Pricing in context
How System Labs's monthly price sits against the category median and the cheapest provider we track.
What we like
- Publishes a standing monthly price on the lander itself rather than hiding it behind an intake quiz
- A compounded GLP-1/GIP dual agonist — the same class as tirzepatide
- LegitScript-verified, with licensed US clinicians and pharmacy-sourced, lab-tested preparations
- Names its medical board in public — Dr. Marc Gruner, Dr. Jonathan Hinds and Dr. Gregory Tennant — with no insurance required and no membership or per-visit fee
The caveats
- The advertised $99 is a first-month rate only — the standing price is $179/mo, and we rank it on the standing price
- GLP-1 is a sideline here: the catalog is built around NAD+, glutathione, sermorelin and MIC-B12
- One molecule only: the single product is a tirzepatide-class GLP-1/GIP and there is no semaglutide SKU at any price, no oral route and no brand-name option
- The pharmacy partner is not publicly named and the states served are not published anywhere — one clinician being “licensed in all 50 states” is a fact about him, not a coverage claim
Who it's for — and who should skip it
System Labs is for people already drawn to a longevity clinic's wider peptide menu who want a dual-agonist GLP-1 alongside it, and who will read past the first-month price.
Skip it if that doesn't sound like you. A closer fit may be Sprout Health (Match Score 76) — or take the quiz to see where System Labs lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
System Labs against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | System Labsthis provider | CoreAge Rxour #1 | Sprout Healthclosest scorer |
|---|---|---|---|
| Sema price | Not offered | $99/mo at every dose | $325/mo |
| Coverage | Not disclosed | All 50 states | 44 states — list not disclosed |
| Formulary | Injectable | Injectable | Injectable + brand |
| Match Score | 76 · C | 91 · A− | 76 · C |
System Labs, answered
Is System Labs legit?
Yes — System Labs is LegitScript-certified, a third-party check that a telehealth pharmacy operates within the rules. Like most programs here it dispenses compounded GLP-1s, which are made by a licensed pharmacy but aren't FDA-approved; confirm your prescriber is US-licensed at intake.
How much does System Labs cost?
System Labs doesn't sell compounded semaglutide at all, so there is no semaglutide price to compare — it is not on their shelf at any figure. Compounded tirzepatide is listed from $179/mo standing. If semaglutide is what you came for, you need a different provider.
Does System Labs ship to my state?
System Labs doesn't publish a full state list, so confirm your state is covered during intake before you pay.
System Labs vs CoreAge Rx — which is better?
Both are in our ranking. System Labs scores 76/100; CoreAge Rx leads our default ranking at 91/100 for its flat nationwide pricing on both molecules and easy cancellation. System Labs can still win for you if its strengths match your priorities: it is built for people already drawn to a longevity clinic's wider peptide menu who want a dual-agonist GLP-1 alongside it, and who will read past the first-month price. Run the quiz to see which comes out ahead for you.
Pricing & state data last verified February 2026 from System Labs's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on System Labs's site. Not medical advice; see our disclosure.
System Labs is a performance-and-longevity clinic first: the catalog is built around NAD+, glutathione, sermorelin and MIC-B12, and the GLP-1 is one lander inside it. What it does prescribe is a compounded GLP-1/GIP dual agonist — the tirzepatide class — and it publishes a standing monthly price on the lander instead of hiding it behind a quiz. Read that lander carefully: the $99 you see first is a first-month rate, labeled “/first mo.” beside a struck-through $179, and $179/mo flat is the standing subscription. We rank it on $179, because that is what month two costs. There is no prepay ladder to weigh — it is month-to-month, pause or cancel from the dashboard — and one price covers every dose. It names its medical board in public, which most of this ranking does not: Dr. Marc Gruner, Dr. Jonathan Hinds and Dr. Gregory Tennant. What it does not give you is choice or coverage: there is no semaglutide product at any price, no oral route and no brand-name option, the dispensing pharmacy is described only as “a certified U.S. pharmacy”, and the states served are published nowhere — one of those doctors being licensed in all 50 states is a fact about him, not a statement about where System Labs can prescribe. Reasonable if you want the wider longevity menu alongside a GLP-1; thin if the GLP-1 is all you came for.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest System Labs here.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match84/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry in this ranking.84/100
- #3Match83/ 100EdenA polished, high-disclosure compounded program with strong nationwide coverage and hands-on support.83/100
- #4Match85/ 100RoA heavyweight telehealth brand with brand-name access and a polished experience — but opaque compounded pricing.85/100
- #5Match85/ 100No BS RXThe highest Transparency score here, and it is not close: twenty-four prices on one public page and four dispensing pharmacies named with street addresses.85/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| MyDrHank#35 | 76 | $253/mo | $354/mo | 44 states — no list published on the site | Alternatives | Visit |
| bmiMD#36 | 76 | $129/mo month-to-month | $179/mo month-to-month | All 50 states | Alternatives | Visit |
| Curex#37 FDA issued Curex a warning letter in September 2025. See FDA's warning-letter database. | 78 | $303/mo | $405/mo | All 50 states | Alternatives | Visit |
| Invigor Medical#38 | 78 | $245/mo | $380/mo | All 50 states | Alternatives | Visit |
| Tyde Wellness#39 | 78 | $271/mo | $379/mo | All 50 states | Alternatives | Visit |
| REMEVi#40 | 78 | $219/mo | $319/mo | All 50 states | Alternatives | Visit |
| PreventiveMD#41 | 78 | $121/mo | $97/mo (as low as, term not published, all-in, compounded) | 36 states | Alternatives | Visit |
| EverSlim#42 | 78 | $113/mo | $136/mo | All 50 states | Alternatives | Visit |
| Rx.com#43 | 78 | $175/mo month-to-month | $285/mo month-to-month | 49 states (its own banner says all 50) | Alternatives | Visit |
| Direct Meds#44 FDA issued directmeds.com, Inc. dba DirectMeds a warning letter in September 2025. See FDA's warning-letter database. | 75 | $297/mo | $399/mo | All 50 states | Alternatives | Visit |
| MadeMed#45 | 75 | $242/mo | $405/mo | Not disclosed | Alternatives | Visit |
| Luvo Health#46 | 75 | $271/mo | $369/mo | Not disclosed | Alternatives | Visit |
| BetterMe Rx#47 | 77 | $303/mo | $412/mo | All 50 states | Alternatives | Visit |
| Amazon One Medical#48 | 77 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Embody#49 | 77 | $79/mo (all doses, promotional rate, compounded) | $129/mo (all doses, promotional rate, compounded) | All 50 states | Alternatives | Visit |
| HealthSource#50 | 77 | $199/mo (all doses, compounded) | $299/mo (all doses, compounded) | All 50 states | Alternatives | Visit |
| LillyDirect Foundayo#51 | 77 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Vitara RX#52 | 77 | $99/mo | $149/mo | 49 states | Alternatives | Visit |
| NextMeds#53 | 77 | $79/mo | $109/mo | All 50 states | Alternatives | Visit |
| KERNX Health#54 | 77 | $129/mo (compounded, plus a one-time consultation fee) | $229/mo (compounded, plus a one-time consultation fee) | All 50 states | Alternatives | Visit |
| AgelessRx#55 | 76 | $239/mo | $349/mo | All 50 states | Alternatives | Visit |
| Henry Meds#56 | 76 | $301/mo | $301/mo | All 50 states | Alternatives | Visit |
| Optimized Health#57 | 76 | $203/mo | $254/mo | MO, IA, KS, UT, WA | Alternatives | Visit |
| Semaglutide Online#58 | 76 | $222/mo | $354/mo | All 50 states | Alternatives | Visit |
System Labs is ranked on our best tirzepatide providers board, scored on the same six factors as every other provider there.