Lyfe Rx review
Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399).
- Scores never bought
- 497 providers tracked
- Every factor auditable
- Updated July 2026
Lyfe Rx earns a Match Score of 62/100 (grade C) and sits #257 of 497 on our board under the balanced default weighting.
- Semaglutide
- $225/mo (compounded)
- Tirzepatide
- $299/mo (compounded)
- Coverage
- Coverage not published
- Brand-name
- Compounded only
- Oral option
- Injectable only
- Verification
- Not independently listed
Best for: People who want use with caution — FDA warning letter on file.
MatchScript's take: Our #257 pick of 497 — a focused, straightforward program, scored on the same six factors as everyone else.
The factor breakdown
Lyfe Rx on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Semaglutide from $225/mo (compounded) puts Budget Fit at a below-par 50 — above the budget tiers.
Limited or undisclosed state coverage can slow your start, for a below-par 60 on Speed to Start.
Lyfe Rx sticks to compounded injectables, for a below-par 66 on Formulary Match.
Support lands at a below-par 71 — lighter, meds-first support.
Flexibility scores a below-par 55 — fewer levers to flex your plan.
Disclosure here is thinner than the top of the board give a below-par 72 on Transparency.
Pricing in context
How Lyfe Rx's monthly price sits against the category median and the cheapest provider we track.
What we like
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
The caveats
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Who it's for — and who should skip it
Choose Lyfe Rx if people who want use with caution — FDA warning letter on file.
Skip it if that doesn't sound like you. A closer fit may be Aquivia Health (Match Score 62) — or take the quiz to see where Lyfe Rx lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
Lyfe Rx against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | Lyfe Rxthis provider | CoreAge Rxour #1 | Aquivia Healthclosest scorer |
|---|---|---|---|
| Sema price | $225/mo (compounded) | $149/mo | $149/mo |
| Coverage | Coverage not published | All 50 states | Coverage not published |
| Formulary | Injectable | Injectable | Injectable + brand |
| Match Score | 62 · C | 91 · A− | 62 · C |
Lyfe Rx, answered
Is Lyfe Rx legit?
Lyfe Rx is a real, operating GLP-1 telehealth program, but we don't find it on the LegitScript registry, so it carries less third-party verification than the certified providers on our board. It dispenses compounded medication, which isn't FDA-approved. Vet the prescriber and pharmacy before you commit.
How much does Lyfe Rx cost?
Lyfe Rx lists compounded semaglutide from $225/mo (compounded) and tirzepatide from $299/mo (compounded) — above our category median of $179/mo. These are the provider's public figures at our last review (July 2026); confirm on their site, since some teaser tiers step up after month one.
Does Lyfe Rx ship to my state?
Lyfe Rx operates in a limited set of states (Coverage not published). If yours isn't on that list, you'll need a nationwide provider instead.
Lyfe Rx vs CoreAge Rx — which is better?
Both are on our board. Lyfe Rx scores 62/100; CoreAge Rx leads our default ranking at 91/100 for its flat nationwide pricing on both molecules and easy cancellation. Lyfe Rx can still win for you if its strengths match your priorities — best for: People who want use with caution — FDA warning letter on file. Run the quiz to see which comes out ahead for you.
Pricing & state data last verified July 2026 from Lyfe Rx's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Lyfe Rx's site. Not medical advice; see our disclosure.
Lyfe Rx earns a Match Score of 62/100 (grade C) and sits #257 of 497 on our board under the balanced default weighting. Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399). Best for: People who want use with caution — FDA warning letter on file. If it isn't the right fit, Aquivia Health is a sensible alternative to weigh next.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest Lyfe Rx on the board.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match88/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry on this board.88/100
- #3Match86/ 100HealthRXA LegitScript-certified, physician-supervised program with a rare oral GLP-1 tablet alongside injectables — both molecules, transparent no-insurance pricing, and a brand-name path.86/100
- #4Match86/ 100ShedRxA weight-focused program that also offers an oral/sublingual route for the needle-averse.86/100
- #5Match88/ 100Ondra HealthNear rock-bottom pricing on both molecules plus some brand access — a rare budget-and-breadth combo, nationwide.88/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| MediRX#258 | 62 | $149/mo (compounded) | $199/mo (compounded) | Coverage not published | Alternatives | Visit |
| Mint Medical Clinic#259 | 62 | $299/mo (compounded) | $299/mo (compounded) | 1 states | Alternatives | Visit |
| Nucore Health#260 | 62 | $299/mo (starting dose, compounded) | $199/mo (microdose tier, compounded) | Coverage not published | Alternatives | Visit |
| Onyx Weight Loss#261 | 62 | $228/mo (starting dose, compounded) | $280/mo (starting dose, compounded) | 8 states | Alternatives | Visit |
| PauseRX#262 | 62 | $199/mo | $249/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Pomegranate Health#263 | 62 | $90/mo (starting dose, compounded) | $166/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Silhouette MD#264 | 62 | $149/mo (compounded) | $299/mo (compounded) | Coverage not published | Alternatives | Visit |
| SnagRx#265 | 62 | $299/mo (starting dose, compounded) | $399/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Spry#266 | 62 | $199/mo (starting dose, compounded) | $299/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Sumbare Wellness#267 | 62 | $199/mo (all doses, compounded) | $199/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| TeleHealth Weight Solutions#268 | 62 | $325/mo (all doses, compounded) | $375/mo | Coverage not published | Alternatives | Visit |
| The Aesthetic Concierge#269 | 62 | $414/mo | Not disclosed | 13 states | Alternatives | Visit |
| The Virtual NP#270 | 62 | Not disclosed | Not disclosed | 7 states | Alternatives | Visit |
| Tru2u#271 | 62 | $225/mo | $345/mo | Coverage not published | Alternatives | Visit |
| Willow#272 | 62 | $299/mo (starting dose, compounded) | $399/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| AquaVita NextGen#273 | 61 | $375/mo (first-month rate, compounded) | $320/mo (starting dose, 3-month plan, compounded) | 5 states | Alternatives | Visit |
| Ark Health#274 | 61 | $1,399/mo (brand Ozempic) | $1,499/mo (brand Mounjaro) | Coverage not published | Alternatives | Visit |
| Aurelius Health Group#275 | 61 | Not disclosed | $199/mo (microdose tier, compounded) | Coverage not published | Alternatives | Visit |
| Avono Health#276 | 61 | $269/mo (compounded) | $349/mo (compounded) | Coverage not published | Alternatives | Visit |
| BeyondMD#277 | 61 | $139/mo (starting dose, compounded) | $209/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Center for Medical Weight Loss (CMWL)#278 | 61 | $149/mo (all doses, compounded) | $239/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| Fitstry#279 | 61 | $179/mo (annual plan, plus a separate fee, compounded) | $269/mo (annual plan, compounded) | Coverage not published | Alternatives | Visit |
| FuturHealth#280 | 61 | $199/mo (compounded) | Not disclosed | Coverage not published | Alternatives | Visit |
| HealthOn#281 | 61 | $189/mo (starting dose, 12-month plan, compounded) | $290/mo (starting dose, 12-month plan, compounded) | Coverage not published | Alternatives | Visit |