Lyfe Rx review: price, pros & cons
Lyfe RX connects patients with licensed providers for compounded semaglutide and tirzepatide, supplies and shipping, with one-time and subscription options and a separate refund policy to read before purchase.
Regulatory notice
FDA issued Lyfe Rx a warning letter in September 2025. You can read it in FDA's warning-letter database. We still list Lyfe Rx, and we may earn a commission if you start care through the link on this page.
- Scores never bought
- 599 providers tracked
- Every factor auditable
Lyfe RX offers compounded semaglutide and tirzepatide through online provider review, with medication, supplies, messaging and shipping described as included.
- Semaglutide
- Not disclosed
- Tirzepatide
- Not disclosed
- Coverage
- Confirm availability in your state
- Brand-name
- Not listed
- Oral option
- Not listed
- Verification
- Not independently listed
Best for: People who want flexible ordering and online provider contact, and will confirm the selected protocol’s supply length, price and cancellation deductions before checkout.
MatchScript's take: Lyfe offers several order cadences, but the selected treatment’s monthly price and nonrefundable consultation deductions need confirming first.
The factor breakdown
Lyfe Rx on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Starting collection figures do not establish your complete monthly charge or supply length; confirm the selected protocol’s bill and cancellation deductions.
Online intake with provider review and pharmacy dispatch after authorization; confirm current eligibility and timing for your state.
Compounded injectable semaglutide and tirzepatide plus a wider wellness and peptide menu; no current oral GLP-1 or brand-name offer established.
Licensed-provider review, included messaging and consultation or lab review for selected protocols provide continuing clinical access.
One-time and recurring cadences with account changes, but filled prescriptions, prepaid plans and consultation charges have refund limitations.
Describes included services and refund deductions, but final selected-plan pricing, supply duration and pharmacy identities need clarification.
Pricing in context
How Lyfe Rx's monthly price sits against the category median and the cheapest provider we track.
| Monthly price | Semaglutide | Tirzepatide |
|---|---|---|
| Lyfe Rxthis providerVisit | Not disclosed | Not disclosed |
| Category median240 tracked | $190/mo | $259/mo |
| Cheapest trackedMondaeVisit | $87/mo | $126/mo |
For a fair comparison, check the full cost of semaglutide or tirzepatide, including care fees, dose changes and the amount due at each renewal.
What we found on their site
Read on Lyfe Rx's own website in October 2026. Quoted text is theirs.
- The treatment description includes "provider review, fully prepared protocol, free shipping & medical supplies" in its price.
- It describes "No membership" rather than adding a separate access subscription.
- The refund policy states "All sales are final" once the prescription is filled or shipped.
What we like
- Offers separate compounded semaglutide and tirzepatide injection protocols with clinician review required before authorization
- Says its treatment price includes provider review, prepared medication, supplies and free delivery without a separate membership fee
- Provides one-time, monthly and quarterly options for many protocols, with cadence changes through the account
- Includes provider messaging and says some protocols can use laboratory testing or a professional consultation when needed
- Publishes a refund policy explaining what happens before and after a prescription is filled, rather than leaving every cancellation condition unstated
The caveats
- Collection cards use starting figures, while product pages do not establish one complete public month-to-month price and supply length for each molecule
- The refund policy lists a $40 standard consultation fee and a $70 live-visit fee if applicable; confirm which deductions apply before canceling
- Filled or shipped prescriptions cannot be returned or refunded, and prepaid packages and subscriptions have additional nonrefundability language
- The product menu combines prescription treatment and nonprescription wellness supplements; confirm the exact prescribed formulation rather than assuming all weight-loss products are medication
- Pharmacies are described as licensed 503A partners without a named dispensing partner on the treatment pages
- No complete current medication-specific state list or brand-name GLP-1 alternative is established on the public product pages
Lyfe RxCheck the current price and eligibility on their site.
Visit Lyfe RxWho it's for — and who should skip it
Lyfe Rx is for people who want flexible ordering and online provider contact, and will confirm the selected protocol’s supply length, price and cancellation deductions before checkout.
Skip it if that doesn't sound like you. A closer fit may be SkinnyRx (Match Score 64) — or take the quiz to see where Lyfe Rx lands for your priorities.
Before you choose care
What semaglutide costs. Compare medication costs, ongoing fees and prepaid plans before choosing care.
What tirzepatide costs. See how dose, medication type and billing terms affect the total price.
Compounded vs. brand-name GLP-1s. Learn how approval, evidence and pharmacy oversight differ between these options.
How to choose a provider. Compare clinical support, pharmacy transparency and cancellation terms alongside price.
How it compares to CoreAge Rx & the closest scorer
Lyfe Rx against CoreAge Rx and the provider that scores closest to it. Green marks the row leader.
| How it compares | Lyfe Rxthis provider | CoreAge Rxfeatured | SkinnyRxclosest scorer |
|---|---|---|---|
| Sema price | Not disclosed | $99/mo at every dose | Not disclosed |
| Coverage | Confirm availability in your state | U.S. only — restrictions vary by state and therapy, list not published | Coverage not published |
| Formulary | Injectable | Injectable | Injectable + oral |
| Match Score | 64 · C | 91 · A− | 64 · C |
Lyfe Rx, answered
Does Lyfe RX charge a separate membership?
It advertises no separate membership or platform fee. Ask for the full selected medication price, supply length and any consultation conditions before payment.
Can I get a refund from Lyfe RX?
Its policy says filled or shipped prescriptions are final. For earlier cancellations it lists $40 standard and $70 synchronous consultation fees if applicable. Confirm which deductions apply to your order.
Pricing & state data come from Lyfe Rx's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Lyfe Rx's site. Not medical advice; see our disclosure.
Lyfe RX offers compounded semaglutide and tirzepatide through online provider review, with medication, supplies, messaging and shipping described as included. Many protocols can be purchased once or on a monthly or quarterly cadence, which may appeal if you dislike a separate membership. The public collection uses starting prices, however, and the product pages do not establish one complete standing monthly bill and supply duration for each medication. Cancellation also has limits: the refund policy allows consultation deductions before fulfillment and says filled or shipped prescriptions are final. Prepaid subscriptions have further restrictions. Confirm your prescribed formulation, pharmacy, recurring charge and cancellation deadline together. Lyfe is worth considering for flexible ordering, provided the written terms match how often you expect to receive treatment.
Compare with other providers
Five more providers to compare (providers we have a commercial relationship with are listed first), then the 24 programs that sit nearest Lyfe Rx here.
- Match91/ 100CoreAge RxCompounded semaglutide at $99 and tirzepatide at $149 a month, the same price at every dose, with no membership fee and a full refund if the doctor doesn't approve you.91/100
- Match86/ 100EdenCompounded semaglutide at $99 and tirzepatide at $129 a month at every dose, with care, coaching and shipping included, a brand-name Wegovy option, and medication from Eden's own pharmacy network.86/100
- Match81/ 100yourEraA personalized-health brand selling compounded semaglutide and tirzepatide alongside NAD+, sermorelin and microdosing protocols, with an optional coaching-and-labs bundle, nationwide.81/100
- Match80/ 100HealthRXA LegitScript-certified program selling compounded semaglutide and tirzepatide on one flat plan price — consult, medication and overnight shipping included — with a full refund if a provider doesn't approve you.80/100
- Match80/ 100ShedRxCompounded semaglutide and tirzepatide as injections, oral drops or lozenges, plus brand-name Wegovy, Zepbound and the Foundayo pill — month to month or cheaper on longer plans.80/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| Human+ | 64 | Not disclosed | Not disclosed | 50 states and D.C. claimed; live visits required in some states | Alternatives | Visit |
| iThriveMD | 64 | Not disclosed | Not disclosed | California and Arizona clinics; confirm telehealth eligibility | Alternatives | Visit |
| Premium Health | 64 | $275/mo (starting dose) | $445/mo (starting dose) | Confirm your state before enrollment | Alternatives | Visit |
| Aurelius Health Group | 64 | Not disclosed | $199/mo (microdose program) | State eligibility confirmed during intake | Alternatives | Visit |
| Harmony Wellness Clinic | 64 | Not disclosed | Not disclosed | Clinician-dependent state list; confirm at booking | Alternatives | Visit |
| CaliberRx | 64 | Not disclosed | Not disclosed | 46 states and DC; excludes AL, MA, RI and VT | Alternatives | Visit |
| Medi-Weightloss | 64 | Not disclosed | Not disclosed | Eligibility must be confirmed before enrollment | Alternatives | Visit |
| Prime Health | 64 | Not disclosed | Not disclosed | The main page states US availability except Louisiana; confirm current eligibility | Alternatives | Visit |
| Whoosh Wellness | 64 | Not disclosed | Not disclosed | Eligibility must be confirmed before enrollment | Alternatives | Visit |
| Stealth Health | 64 | Not disclosed | Not disclosed | Eligibility must be confirmed before enrollment | Alternatives | Visit |
| TeleDocs360 | 64 | $299/mo | $399/mo (starting dose) | Coverage not published | Alternatives | Visit |
| MDExam | 64 | Not disclosed | Not disclosed | Confirm state and prescription eligibility | Alternatives | Visit |
| Wellspring Longevity Clinic | 64 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Blue Haven RX | 64 | Not disclosed | Not disclosed | Confirm state and medication eligibility | Alternatives | Visit |
| Bayan Health | 64 | Not disclosed | Not disclosed | All 50 states, subject to treatment and pharmacy restrictions | Alternatives | Visit |
| Vital Step | 64 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| LifeVine Wellness | 64 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| New Wave Health | 64 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Eviora MD | 64 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Meli Health | 64 | $229/mo | $299/mo | 49 US states; excludes California | Alternatives | Visit |
| System Labs | 61 | Not offered | Not disclosed | All 50 states | Alternatives | Visit |
| Vaylen | 63 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Embody | 63 | Not disclosed | Not disclosed | Not published — certain states only; the list is available from support | Alternatives | Visit |
| Queen RX | 63 | Not disclosed | Not disclosed | 44 states (excludes CA, KS, LA, MS, NM, WV) | Alternatives | Visit |