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Ranked #166 of 537 · Grade C

PCOS Sisters review

PCOS Sisters is a women's telehealth clinic focused on polycystic ovary syndrome that offers a GLP-1 weight and metabolic management program for 150 dollars per month with membership required.

Visit PCOS Sisters Or see your best match We may earn a commission if you start care through some of these links, at no extra cost to you. What we write about a provider is the same either way, providers we have a commercial relationship with are listed first on most boards, and every Match Score is computed from the six published factor sub-scores regardless. See our disclosure.

Semaglutide here is $150/mo (plus a separate fee, compounded) — $49 below our category median of $199.

Semaglutide
$150/mo (plus a separate fee, compounded)
Tirzepatide
$150/mo (plus a separate fee, compounded)
Coverage
12 states
Brand-name
Yes
Oral option
Yes
Verification
Not independently listed

Best for: Women with pcos seeking GLP-1 weight and metabolic care.

MatchScript's take: Our #166 pick of 537 — priced at or below the category median.

The factor breakdown

PCOS Sisters on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.

Budget Fit60/100

Semaglutide from $150/mo (plus a separate fee, compounded) puts Budget Fit at a below-par 60 — above the budget tiers.

Speed to Start60/100

Limited or undisclosed state coverage can slow your start, for a below-par 60 on Speed to Start.

Formulary Match90/100

PCOS Sisters adds an oral/sublingual route and brand-name access on top of injectables, for a strong 90 on Formulary Match.

Support Level74/100

Support lands at a below-par 74 — lighter, meds-first support.

Flexibility41/100

Flexibility scores a below-par 41 — fewer levers to flex your plan.

Transparency85/100

Open pricing and coverage detail put Transparency at a solid 85.

Pricing in context

How PCOS Sisters's monthly price sits against the category median and the cheapest provider we track.

Monthly priceSemaglutideTirzepatide
PCOS Sistersthis providerVisit $150/mo (plus a separate fee, compounded)$49 vs median$150/mo (plus a separate fee, compounded)$124 vs median
Category median430 tracked$199/mo$274/mo
Cheapest trackedMondaeVisit $87 per 28 days (13 charges a year)$126 per 28 days (13 charges a year)

What we like

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

The caveats

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Who it's for — and who should skip it

PCOS Sisters is for women with pcos seeking GLP-1 weight and metabolic care.

Skip it if that doesn't sound like you. A closer fit may be Synergy Rx (Match Score 68) — or take the quiz to see where PCOS Sisters lands for your priorities.

See every alternative to PCOS Sisters.

How it compares to CoreAge Rx & the closest scorer

PCOS Sisters against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.

How it comparesPCOS Sistersthis providerCoreAge Rxour #1Synergy Rxclosest scorer
Sema price$150/mo (plus a separate fee, compounded)$99/mo at every dose$249/mo
Coverage12 statesAll 50 statesAll 50 states
FormularyInjectable + oral + brandInjectableInjectable + oral
Match Score68 · C91 · A−68 · C

PCOS Sisters, answered

Is PCOS Sisters legit?

PCOS Sisters is a real, operating GLP-1 telehealth program. LegitScript certification is the third-party check worth asking for — look for the seal on their site and confirm your prescriber is US-licensed at intake. Like most programs here it dispenses compounded GLP-1s, which are made by a licensed pharmacy but aren't FDA-approved.

How much does PCOS Sisters cost?

PCOS Sisters lists compounded semaglutide from $150/mo (plus a separate fee, compounded) and tirzepatide from $150/mo (plus a separate fee, compounded) — below our category median of $199/mo. These are the provider's public figures at our last review (July 2026); confirm on their site, since some teaser tiers step up after month one.

Does PCOS Sisters ship to my state?

PCOS Sisters operates in a limited set of states (12 states). If yours isn't on that list, you'll need a nationwide provider instead.

PCOS Sisters vs Synergy Rx — which should I pick?

They score within a few points of each other: PCOS Sisters at 68/100 and Synergy Rx at 68/100, so neither wins on the headline number. PCOS Sisters is the better fit for women with pcos seeking GLP-1 weight and metabolic care. Synergy Rx suits people who value 24/7 access to a care team and want to see a number before starting an intake, even an incomplete one. Run the quiz and the weighting shifts to whichever of those matters more to you.

Pricing & state data last verified July 2026 from PCOS Sisters's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on PCOS Sisters's site. Not medical advice; see our disclosure.

Verdict · Grade C · 68/100

Semaglutide here is $150/mo (plus a separate fee, compounded) — $49 below our category median of $199. Tirzepatide is $150/mo (plus a separate fee, compounded). Its strongest suit is the range of medication it offers. Best suited to women with pcos seeking GLP-1 weight and metabolic care. If that is not you, Synergy Rx is the closest thing to it here.

Compare with other providers

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PCOS Sisters is ranked on our best semaglutide providers, best tirzepatide providers, best GLP-1 programs, best brand-name GLP-1 providers and best oral GLP-1 providers boards, scored on the same six factors as every other provider there.

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