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Match Score 66 · Grade C

PCOS Sisters review: price, pros & cons

By MatchScript EditorialUpdated

A telehealth clinic for women with PCOS, run by nurse practitioners who specialize in it, offering GLP-1 management inside a $150-a-month membership, with medication billed separately by its partner pharmacies.

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PCOS Sisters is a specialist clinic first and a GLP-1 provider second.

Semaglutide
Not disclosed
Tirzepatide
Not disclosed
Coverage
9 states (AZ, FL, GA, NM, OR, TX, UT, VA, WA)
Brand-name
Not listed
Oral option
Yes
Verification
Not independently listed

Best for: Women with PCOS who want GLP-1 treatment managed around insulin resistance and hormones, with frequent video visits and a fitness program built in.

MatchScript's take: Specialist PCOS care with GLP-1 management included — but the $150 membership is not the whole bill, since medication is extra.

The factor breakdown

PCOS Sisters on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.

Budget Fit45/100

The $150 membership covers care only and medication is billed separately at a price the site does not publish, so Budget Fit sits just under the unpriced anchor at 45.

Speed to Start58/100

Limited or undisclosed state coverage can slow your start, for a below-par 58 on Speed to Start.

Formulary Match77/100

PCOS Sisters lists an oral/sublingual route, for a middling 77 on Formulary Match.

Support Level88/100

Unlimited video visits and messages with PCOS-focused nurse practitioners, lab ordering and a fitness program put Support Level at 88.

Flexibility58/100

Flexibility scores 58/100 in our comparison. Check the renewal, cancellation and refund terms before paying; dose changes require a prescriber's approval.

Transparency70/100

The membership price and pharmacies are published, but the medication cost is not and the state list differs between pages.

Pricing in context

How PCOS Sisters's monthly price sits against the category median and the cheapest provider we track.

Monthly priceSemaglutideTirzepatide
PCOS Sistersthis providerVisit Not disclosedNot disclosed
Category median240 tracked$190/mo$259/mo
Cheapest trackedMondaeVisit $87/mo$126/mo

For a fair comparison, check the full cost of semaglutide or tirzepatide, including care fees, dose changes and the amount due at each renewal.

What we found on their site

Read on PCOS Sisters's own website in October 2026. Quoted text is theirs.

  • The FAQ answers "Do you offer GLP-1 prescriptions?" with "Yes. A membership is required for a GLP-1 prescription. Our GLP-1 prescriptions start at $150/mo."
  • It also says "the cost of labs, medications, and imaging are not included with the $75 self pay visit charge or membership fees".
  • Its state answer reads "We currently provide PCOS treatment in AZ, CT, FL, GA, HI, NM, NY, TX, UT, VA, & WA.", while the service-area page lists Arizona, Florida, Georgia, New Mexico, Oregon, Texas, Utah, Virginia and Washington.

What we like

  • Care built around PCOS by nurse practitioners who specialize in it, with unlimited 30-minute video visits and messaging in the membership
  • The membership includes lab ordering, a personalized diet and exercise plan, the PCOS Sisters Fitness app and a peer-support community
  • Names its partner pharmacies, Strive Pharmacy and Striker Pharmacy, with addresses and phone numbers
  • Semaglutide and other GLP-1s, including microdosing and oral GLP-1 options, chosen around insulin resistance
  • A free 10-minute phone consult and same-week appointments

The caveats

  • The $150 a month is the membership; medication, labs and imaging are billed separately by the pharmacy or lab, so the full monthly cost is not published
  • Serves only nine states on its service-area page, and its FAQ gives a different list that adds Connecticut, Hawaii and New York and leaves out Oregon
  • A basic discounted PCOS lab workup is about $335 on top of the membership
  • Insurance does not cover the membership, and Medicare and Medicaid are not accepted
  • Built for women with PCOS, so it is not a general weight-loss service

PCOS SistersCheck the current price and eligibility on their site.

Visit PCOS Sisters

Who it's for — and who should skip it

PCOS Sisters is for women with PCOS who want GLP-1 treatment managed around insulin resistance and hormones, with frequent video visits and a fitness program built in.

Skip it if that doesn't sound like you. A closer fit may be MEDGm (Match Score 66) — or take the quiz to see where PCOS Sisters lands for your priorities.

See every alternative to PCOS Sisters.

Before you choose care

What semaglutide costs. Compare medication costs, ongoing fees and prepaid plans before choosing care.

What tirzepatide costs. See how dose, medication type and billing terms affect the total price.

Oral GLP-1s vs. injections. Understand the differences between approved oral medicines, compounded forms and injections.

Compounded vs. brand-name GLP-1s. Learn how approval, evidence and pharmacy oversight differ between these options.

How it compares to CoreAge Rx & the closest scorer

PCOS Sisters against CoreAge Rx and the provider that scores closest to it. Green marks the row leader.

How it comparesPCOS Sistersthis providerCoreAge RxfeaturedMEDGmclosest scorer
Sema priceNot disclosed$99/mo at every dose$299/mo
Coverage9 states (AZ, FL, GA, NM, OR, TX, UT, VA, WA)U.S. only — restrictions vary by state and therapy, list not publishedAll 50 states plus Washington, D.C.
FormularyInjectable + oralInjectableInjectable + oral
Match Score66 · C91 · A−66 · C

PCOS Sisters, answered

Does PCOS Sisters offer GLP-1s?

Yes, but only to members. Its FAQ says a membership is required for a GLP-1 prescription, and GLP-1 management is built into the membership, with semaglutide and other GLP-1s, microdosing and oral options chosen around PCOS and insulin resistance.

How much does PCOS Sisters cost?

GLP-1 management through the membership is $150 a month, and a one-time evaluation visit is $75. Medication, labs and imaging are not included — they are billed by the pharmacy, lab or imaging center — and a basic discounted PCOS lab workup is about $335.

Which states does PCOS Sisters serve?

Its service-area page lists Arizona, Florida, Georgia, New Mexico, Oregon, Texas, Utah, Virginia and Washington. Its FAQ gives a different list that includes Connecticut, Hawaii and New York, so confirm your state before booking.

Does PCOS Sisters take insurance?

Only for evaluation visits for Georgia patients with Aetna or United Healthcare. Insurance does not cover the membership, and Medicare and Medicaid are not accepted, though you can use your insurance for labs, imaging and prescriptions.

Pricing & state data come from PCOS Sisters's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on PCOS Sisters's site. Not medical advice; see our disclosure.

Verdict · Grade C · 66/100

PCOS Sisters is a specialist clinic first and a GLP-1 provider second. Its nurse practitioners focus on PCOS, and the $150-a-month membership buys a lot of contact: unlimited 30-minute video visits, unlimited messages, lab ordering, a personalized diet and exercise plan, its own fitness app and a peer community. GLP-1 treatment — semaglutide and others, including microdosing and oral options — is managed with insulin resistance in mind, and it names its partner pharmacies, Strive and Striker. What it does not publish is the medication price: the membership covers care, while the drug, labs and imaging are billed separately, and a basic lab workup alone is about $335. Coverage is limited to a handful of states, and two of its own pages list them differently. Bottom line: a strong fit for women with PCOS in a served state; ask for the pharmacy's monthly price before you join.

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