Signos review
Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with…
- Scores never bought
- 497 providers tracked
- Every factor auditable
- Updated July 2026
Signos earns a Match Score of 57/100 (grade C) and sits #355 of 497 on our board under the balanced default weighting.
- Semaglutide
- $199/mo (6-month plan, compounded)
- Tirzepatide
- $199/mo (starting dose, compounded)
- Coverage
- Coverage not published
- Brand-name
- Compounded only
- Oral option
- Injectable only
- Verification
- Not independently listed
Best for: People who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.
MatchScript's take: Our #355 pick of 497 — a focused, straightforward program, scored on the same six factors as everyone else.
The factor breakdown
Signos on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Semaglutide from $199/mo (6-month plan, compounded) puts Budget Fit at a below-par 43 — above the budget tiers.
Limited or undisclosed state coverage can slow your start, for a below-par 62 on Speed to Start.
Signos sticks to compounded injectables, for a below-par 66 on Formulary Match.
Support lands at a solid 82 — solid, standard support.
Flexibility scores a below-par 20 — fewer levers to flex your plan.
Disclosure here is thinner than the top of the board give a below-par 72 on Transparency.
Pricing in context
How Signos's monthly price sits against the category median and the cheapest provider we track.
What we like
- Bundles compounded GLP-1 (semaglutide) with an FDA-cleared CGM and app — glucose-guided weight loss, not just medication
- Starting at $199/mo on a 6-month program, with the CGM included at no extra cost
- Free rapid shipping; HSA/FSA eligible
- Real-time glucose insights and app coaching to help sustain results after GLP-1
The caveats
- Compounded GLP-1s are not FDA-approved finished products
- Headline price is a 6-month-program rate, not month-to-month
- Only semaglutide is shown in the program; tirzepatide availability is not confirmed
- Compounding pharmacy partner and state availability are not published on the landing page
Who it's for — and who should skip it
Choose Signos if people who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app.
Skip it if that doesn't sound like you. A closer fit may be Bioverse (Match Score 57) — or take the quiz to see where Signos lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
Signos against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | Signosthis provider | CoreAge Rxour #1 | Bioverseclosest scorer |
|---|---|---|---|
| Sema price | $199/mo (6-month plan, compounded) | $149/mo | $129/mo (starting dose, compounded) |
| Coverage | Coverage not published | All 50 states | Coverage not published |
| Formulary | Injectable | Injectable | Injectable + brand |
| Match Score | 57 · C | 91 · A− | 57 · C |
Signos, answered
Is Signos legit?
Signos is a real, operating GLP-1 telehealth program, but we don't find it on the LegitScript registry, so it carries less third-party verification than the certified providers on our board. It dispenses compounded medication, which isn't FDA-approved. Vet the prescriber and pharmacy before you commit.
How much does Signos cost?
Signos lists compounded semaglutide from $199/mo (6-month plan, compounded) and tirzepatide from $199/mo (starting dose, compounded) — above our category median of $179/mo. These are the provider's public figures at our last review (July 2026); confirm on their site, since some teaser tiers step up after month one.
Does Signos ship to my state?
Signos operates in a limited set of states (Coverage not published). If yours isn't on that list, you'll need a nationwide provider instead.
Signos vs CoreAge Rx — which is better?
Both are on our board. Signos scores 57/100; CoreAge Rx leads our default ranking at 91/100 for its flat nationwide pricing on both molecules and easy cancellation. Signos can still win for you if its strengths match your priorities — best for: People who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app. Run the quiz to see which comes out ahead for you.
Pricing & state data last verified July 2026 from Signos's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Signos's site. Not medical advice; see our disclosure.
Signos earns a Match Score of 57/100 (grade C) and sits #355 of 497 on our board under the balanced default weighting. Signos (Signos+) is a metabolic-health platform that bundles clinician-prescribed compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor (CGM) and app — pairing the medication with… Best for: People who want pairing compounded GLP-1 (semaglutide) with an FDA-cleared continuous glucose monitor and app. If it isn't the right fit, Bioverse is a sensible alternative to weigh next.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest Signos on the board.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match88/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry on this board.88/100
- #3Match86/ 100HealthRXA LegitScript-certified, physician-supervised program with a rare oral GLP-1 tablet alongside injectables — both molecules, transparent no-insurance pricing, and a brand-name path.86/100
- #4Match86/ 100ShedRxA weight-focused program that also offers an oral/sublingual route for the needle-averse.86/100
- #5Match88/ 100Ondra HealthNear rock-bottom pricing on both molecules plus some brand access — a rare budget-and-breadth combo, nationwide.88/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| TeleSlim Clinic#356 | 57 | Not disclosed | Not disclosed | 6 states | Alternatives | Visit |
| Voxy#357 | 57 | $179/mo (compounded) | $299/mo (compounded) | Coverage not published | Alternatives | Visit |
| EOS Health#358 | 56 | $199/mo (compounded) | $289/mo (compounded) | 40 states | Alternatives | Visit |
| Form Health#359 | 56 | $1,350/mo (starting dose, brand-name) | $1,350/mo (starting dose, brand-name) | All 50 states | Alternatives | Visit |
| LevelUp Rx#360 | 56 | $150/mo (starting dose, compounded) | $250/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| LVNG RX#361 | 56 | $149/mo (starting dose, compounded) | $249/mo (microdose tier, starting dose, compounded) | Coverage not published | Alternatives | Visit |
| MDLive#362 | 56 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Medivive#363 | 56 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Metabolyz#364 | 56 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| QuickMD#365 | 56 | $279/mo (compounded) | Not disclosed | Coverage not published | Alternatives | Visit |
| Remi Meds#366 | 56 | $249/mo (0.25 mg dose, compounded) | $349/mo (2.25 mg dose, compounded) | Coverage not published | Alternatives | Visit |
| SkyRx#367 | 56 | $199/mo (all doses, 12-month plan, compounded) | Not disclosed | Coverage not published | Alternatives | Visit |
| Strive Pharmacy#368 | 56 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Vital Edge#369 | 56 | $350/mo (compounded) | $450/mo (compounded) | Coverage not published | Alternatives | Visit |
| Vyora Wellness#370 | 56 | $299/mo (compounded) | $399/mo (compounded) | Coverage not published | Alternatives | Visit |
| Balanced Hormone Health#371 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Good Life Meds#372 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| HealthHub#373 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| HumeCare+#374 | 55 | $199/mo (starting dose, compounded) | Not disclosed | Coverage not published | Alternatives | Visit |
| Klarity Health#375 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Medi-Weightloss#376 | 55 | $199/mo (promotional rate, brand-name) | Not disclosed | Coverage not published | Alternatives | Visit |
| Meto#377 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Mevo Health#378 | 55 | $199/mo (all doses, compounded) | $259/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| Nu Image Medical#379 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |