Cost Plus Drugs review
Mark Cuban's transparent-pricing online pharmacy.
- Scores never bought
- 537 providers tracked
- Every factor auditable
- Updated July 2026
Semaglutide here is $279/mo (brand Ozempic) — $80 above our category median of $199.
- Semaglutide
- $279/mo (brand Ozempic)
- Tirzepatide
- Not disclosed
- Coverage
- All 50 states
- Brand-name
- Yes
- Oral option
- Injectable only
- Verification
- Not independently listed
Best for: People who want the cheapest transparent-pricing brand-name Ozempic channel.
MatchScript's take: Our #247 pick of 537 — confirmed nationwide access.
The factor breakdown
Cost Plus Drugs on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Semaglutide from $279/mo (brand Ozempic) puts Budget Fit at a below-par 45 — above the budget tiers.
Confirmed all-50-state access means it can usually prescribe within days, for a strong 88 on Speed to Start.
Cost Plus Drugs adds brand-name access on top of injectables, for a below-par 66 on Formulary Match.
Support lands at a below-par 64 — lighter, meds-first support.
Flexibility scores a below-par 55 — fewer levers to flex your plan.
Thinner public disclosure than the top of the ranking keeps Transparency at a below-par 68.
Pricing in context
How Cost Plus Drugs's monthly price sits against the category median and the cheapest provider we track.
What we found on their site
Loaded costplusdrugs.com/medications/?search=ozempic on August 2026. Quoted text is theirs.
- A search for Ozempic on the Cost Plus Drugs medication catalogue returned no price on the results page at the time of checking.
What we like
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
The caveats
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
Who it's for — and who should skip it
Cost Plus Drugs is for people who want the cheapest transparent-pricing brand-name Ozempic channel.
Skip it if that doesn't sound like you. A closer fit may be SkinnyRx (Match Score 64) — or take the quiz to see where Cost Plus Drugs lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
Cost Plus Drugs against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | Cost Plus Drugsthis provider | CoreAge Rxour #1 | SkinnyRxclosest scorer |
|---|---|---|---|
| Sema price | $279/mo (brand Ozempic) | $99/mo at every dose | $354/mo |
| Coverage | All 50 states | All 50 states | 47 states + DC |
| Formulary | Injectable + brand | Injectable | Injectable + oral |
| Match Score | 64 · C | 91 · A− | 64 · C |
Cost Plus Drugs, answered
Is Cost Plus Drugs legit?
Cost Plus Drugs is a real, operating GLP-1 telehealth program. LegitScript certification is the third-party check worth asking for — look for the seal on their site and confirm your prescriber is US-licensed at intake. It dispenses FDA-approved brand-name medication rather than the compounded formulas most programs here sell, which is why its pricing sits higher.
How much does Cost Plus Drugs cost?
Cost Plus Drugs lists compounded semaglutide from $279/mo (brand Ozempic) — above our category median of $199/mo. These are the provider's public figures at our last review (July 2026); confirm on their site, since some teaser tiers step up after month one.
Does Cost Plus Drugs ship to my state?
Yes — Cost Plus Drugs reports availability in all 50 states, so most people can start within days.
Cost Plus Drugs vs SkinnyRx — which should I pick?
They score within a few points of each other: Cost Plus Drugs at 64/100 and SkinnyRx at 64/100, so neither wins on the headline number. Cost Plus Drugs is the better fit for people who want the cheapest transparent-pricing brand-name Ozempic channel. SkinnyRx suits shoppers who want a tablet as well as an injection on either molecule, and who read the term attached to an advertised rate before they read the number. Run the quiz and the weighting shifts to whichever of those matters more to you.
Pricing & state data last verified July 2026 from Cost Plus Drugs's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Cost Plus Drugs's site. Not medical advice; see our disclosure.
Semaglutide here is $279/mo (brand Ozempic) — $80 above our category median of $199. It scores highest on how quickly you can start. Best suited to people who want the cheapest transparent-pricing brand-name Ozempic channel. If that is not you, SkinnyRx is the closest thing to it here.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest Cost Plus Drugs here.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match84/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry in this ranking.84/100
- #3Match83/ 100EdenA polished, high-disclosure compounded program with strong nationwide coverage and hands-on support.83/100
- #4Match85/ 100RoA heavyweight telehealth brand with brand-name access and a polished experience — but opaque compounded pricing.85/100
- #5Match85/ 100No BS RXThe highest Transparency score here, and it is not close: twenty-four prices on one public page and four dispensing pharmacies named with street addresses.85/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| Curve#248 | 64 | $175/mo (compounded) | $225/mo (compounded) | All 50 states | Alternatives | Visit |
| Framework#249 | 64 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| GetRelief Rx#250 | 64 | $212/mo | $364/mo | Coverage not published | Alternatives | Visit |
| Tell Her Doc#251 | 64 | $269/mo (microdose tier, plus a separate fee, compounded) | Not disclosed | All 50 states | Alternatives | Visit |
| Arc-1#252 | 64 | $200/mo (0.5 mg dose, compounded) | $200/mo (2.5 mg dose, compounded) | Coverage not published | Alternatives | Visit |
| WePeptideRx#253 | 64 | $189/mo | $202/mo | Coverage not published | Alternatives | Visit |
| TelePeptide#254 | 64 | $199/mo (starting dose, annual plan, compounded oral) | $249/mo | Coverage not published | Alternatives | Visit |
| VitaFusions IV#255 | 64 | $149/mo (all doses, plus a separate fee, compounded) | $192/mo | Coverage not published | Alternatives | Visit |
| Roen Rx#256 FDA issued Roen Health, Inc. dba RoenRx a warning letter in June 2026. See FDA's warning-letter database. | 64 | $151/mo (3-month plan, plus a separate fee, compounded) | $456/mo | Coverage not published | Alternatives | Visit |
| Alinwell#257 | 64 | $249/mo (charged every 30 days; the advertised rate is a first-month price) | $299/mo (charged every 30 days; the advertised rate is a first-month price) | All 50 states | Alternatives | Visit |
| Boston Medical Group#258 | 63 | $325/mo | $253/mo | 7 states | Alternatives | Visit |
| WeightRx#259 | 63 | $250/mo (compounded) | $83/mo (term not published, compounded) | Coverage not published | Alternatives | Visit |
| HeliMeds#260 | 63 | $260/mo | $162/mo | Coverage not published | Alternatives | Visit |
| AZ Health#261 | 63 | $179/mo (all doses, compounded) | $249/mo | Coverage not published | Alternatives | Visit |
| NP2GO#262 | 63 | $183/mo | $283/mo | 40 states | Alternatives | Visit |
| Options Medical Weight Loss#263 | 63 | $271/mo | $379/mo | Coverage not published | Alternatives | Visit |
| Cielo#264 | 63 | $141/mo | $192/mo | Coverage not published | Alternatives | Visit |
| Eloria#265 | 63 | $299/mo | Not disclosed | Coverage not published | Alternatives | Visit |
| AskRx#266 | 63 | $349/mo (all doses, brand-name) | $299/mo (2.5 mg dose, brand-name) | All 50 states | Alternatives | Visit |
| BloomWell Rx#267 | 63 | $202/mo | $253/mo | Coverage not published | Alternatives | Visit |
| Society of You#268 | 63 | $279/mo (promotional rate, compounded) | $425/mo (compounded) | Coverage not published | Alternatives | Visit |
| ARSYNL Rx#269 | 63 | $233/mo (compounded) | $233/mo | Coverage not published | Alternatives | Visit |
| Levers Health#270 | 63 | $251/mo | $402/mo | Coverage not published | Alternatives | Visit |
| LifeRx.md#271 | 63 | $174/mo | $174/mo | All 50 states | Alternatives | Visit |
Cost Plus Drugs is ranked on our best semaglutide providers and best brand-name GLP-1 providers boards, scored on the same six factors as every other provider there.