Cost Plus Drugs review
Mark Cuban's transparent-pricing online pharmacy.
- Scores never bought
- 497 providers tracked
- Every factor auditable
- Updated July 2026
Cost Plus Drugs earns a Match Score of 64/100 (grade C) and sits #214 of 497 on our board under the balanced default weighting.
- Semaglutide
- $279/mo (brand Ozempic)
- Tirzepatide
- Not disclosed
- Coverage
- All 50 states
- Brand-name
- Yes
- Oral option
- Injectable only
- Verification
- Not independently listed
Best for: People who want the cheapest transparent-pricing brand-name Ozempic channel.
MatchScript's take: Our #214 pick of 497 — confirmed nationwide access, scored on the same six factors as everyone else.
The factor breakdown
Cost Plus Drugs on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Semaglutide from $279/mo (brand Ozempic) puts Budget Fit at a below-par 45 — above the budget tiers.
Confirmed all-50-state access means it can usually prescribe within days, for a strong 88 on Speed to Start.
Cost Plus Drugs adds brand-name access on top of injectables, for a below-par 66 on Formulary Match.
Support lands at a below-par 64 — lighter, meds-first support.
Flexibility scores a below-par 55 — fewer levers to flex your plan.
Disclosure here is thinner than the top of the board give a below-par 68 on Transparency.
Pricing in context
How Cost Plus Drugs's monthly price sits against the category median and the cheapest provider we track.
What we like
- Transparent pricing: wholesale cost + 15% markup + $5 pharmacy fee, the same for everyone
- Around $279/mo for branded Ozempic — well below typical retail list prices
- Mark Cuban's PBM-disrupting pharmacy, praised by Forbes Health, Wired, and KFF Health News
- Ships to all 50 states; genuine FDA-approved Novo Nordisk Ozempic, not compounded
- Partnered with 9amHealth so you can get prescribed and fill at Cost Plus pricing
The caveats
- Fulfillment only — no telehealth intake; you need a prescription from an outside clinician
- Ozempic is FDA-indicated for type 2 diabetes, not weight management — weight-loss use is off-label
- Wegovy availability has been spotty — check current stock before assuming it ships
- No compounded semaglutide or tirzepatide — brand only
- No clinical follow-up — side-effect monitoring falls to your prescribing clinician
Who it's for — and who should skip it
Choose Cost Plus Drugs if people who want the cheapest transparent-pricing brand-name Ozempic channel.
Skip it if that doesn't sound like you. A closer fit may be AVARA Rx (Match Score 64) — or take the quiz to see where Cost Plus Drugs lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
Cost Plus Drugs against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | Cost Plus Drugsthis provider | CoreAge Rxour #1 | AVARA Rxclosest scorer |
|---|---|---|---|
| Sema price | $279/mo (brand Ozempic) | $149/mo | $229/mo (starting dose, compounded) |
| Coverage | All 50 states | All 50 states | All 50 states |
| Formulary | Injectable + brand | Injectable | Injectable + brand |
| Match Score | 64 · C | 91 · A− | 64 · C |
Cost Plus Drugs, answered
Is Cost Plus Drugs legit?
Cost Plus Drugs is a real, operating GLP-1 telehealth program, but we don't find it on the LegitScript registry, so it carries less third-party verification than the certified providers on our board. It dispenses compounded medication, which isn't FDA-approved. Vet the prescriber and pharmacy before you commit.
How much does Cost Plus Drugs cost?
Cost Plus Drugs lists compounded semaglutide from $279/mo (brand Ozempic) — above our category median of $179/mo. These are the provider's public figures at our last review (July 2026); confirm on their site, since some teaser tiers step up after month one.
Does Cost Plus Drugs ship to my state?
Yes — Cost Plus Drugs reports availability in all 50 states, so most people can start within days.
Cost Plus Drugs vs CoreAge Rx — which is better?
Both are on our board. Cost Plus Drugs scores 64/100; CoreAge Rx leads our default ranking at 91/100 for its flat nationwide pricing on both molecules and easy cancellation. Cost Plus Drugs can still win for you if its strengths match your priorities — best for: People who want the cheapest transparent-pricing brand-name Ozempic channel. Run the quiz to see which comes out ahead for you.
Pricing & state data last verified July 2026 from Cost Plus Drugs's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Cost Plus Drugs's site. Not medical advice; see our disclosure.
Cost Plus Drugs earns a Match Score of 64/100 (grade C) and sits #214 of 497 on our board under the balanced default weighting. Mark Cuban's transparent-pricing online pharmacy. Best for: People who want the cheapest transparent-pricing brand-name Ozempic channel. If it isn't the right fit, AVARA Rx is a sensible alternative to weigh next.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest Cost Plus Drugs on the board.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match88/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry on this board.88/100
- #3Match86/ 100HealthRXA LegitScript-certified, physician-supervised program with a rare oral GLP-1 tablet alongside injectables — both molecules, transparent no-insurance pricing, and a brand-name path.86/100
- #4Match86/ 100ShedRxA weight-focused program that also offers an oral/sublingual route for the needle-averse.86/100
- #5Match88/ 100Ondra HealthNear rock-bottom pricing on both molecules plus some brand access — a rare budget-and-breadth combo, nationwide.88/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| Curve#215 | 64 | $175/mo (compounded) | $225/mo (compounded) | All 50 states | Alternatives | Visit |
| ElixaMD#216 | 64 | $179/mo (starting dose, first-month rate, compounded) | Not disclosed | Coverage not published | Alternatives | Visit |
| Eloria#217 | 64 | $179/mo (starting dose, plus a separate fee, compounded) | Not disclosed | Coverage not published | Alternatives | Visit |
| Fierce Health#218 | 64 | $297/mo (3-month plan, compounded) | $497/mo (3-month plan, compounded) | 30 states | Alternatives | Visit |
| GetRelief Rx#219 | 64 | $269/mo (9 mg dose, compounded oral) | $179/mo (16 mg dose, compounded oral) | Coverage not published | Alternatives | Visit |
| Heva Health#220 | 64 | $149/mo (compounded) | Not disclosed | Coverage not published | Alternatives | Visit |
| InstaRX#221 | 64 | $199/mo (starting dose, compounded) | $199/mo (starting dose, compounded) | All 50 states | Alternatives | Visit |
| Intimate Rose#222 | 64 | $169/mo (all doses, compounded) | $169/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| Lumen Meds#223 | 64 | Not disclosed | $196/mo (compounded) | Coverage not published | Alternatives | Visit |
| Luvo Health#224 | 64 | $249/mo (compounded) | $339/mo (compounded) | Coverage not published | Alternatives | Visit |
| Medro#225 | 64 | $199/mo (compounded) | $299/mo (compounded) | All 50 states | Alternatives | Visit |
| Nirwana Health#226 | 64 | $149/mo (compounded) | $229/mo (compounded) | Coverage not published | Alternatives | Visit |
| OnlyRx#227 | 64 | $179/mo (starting dose, promotional rate, compounded) | $249/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| PepHaūs#228 | 64 | $152/mo (quarterly plan, compounded) | $246/mo (compounded) | All 50 states | Alternatives | Visit |
| RxPros#229 | 64 | $100/mo (annual plan, compounded) | $145/mo (annual plan, compounded) | Coverage not published | Alternatives | Visit |
| Tell Her Doc#230 | 64 | $269/mo (microdose tier, plus a separate fee, compounded) | Not disclosed | All 50 states | Alternatives | Visit |
| Tuyo Health#231 | 64 | $155/mo | $279/mo | Coverage not published | Alternatives | Visit |
| Velvet Rx#232 | 64 | $299/mo (compounded) | $359/mo (compounded) | Coverage not published | Alternatives | Visit |
| Arc-1#233 | 63 | $200/mo (0.5 mg dose, compounded) | $200/mo (2.5 mg dose, compounded) | Coverage not published | Alternatives | Visit |
| AskRx#234 | 63 | $349/mo (all doses, brand-name) | $299/mo (2.5 mg dose, brand-name) | All 50 states | Alternatives | Visit |
| BloomWell Rx#235 | 63 | $199/mo (starting dose, compounded) | $249/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| boostAGErx#236 | 63 | $95/mo (starting dose, compounded) | $95/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Coivas#237 | 63 | $149/mo (quarterly plan, compounded) | $229/mo (quarterly plan, compounded) | Coverage not published | Alternatives | Visit |
| Framework#238 | 63 | $100/mo (starting dose, compounded) | $100/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |