SkyRx review
SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon.
- Scores never bought
- 497 providers tracked
- Every factor auditable
- Updated July 2026
SkyRx earns a Match Score of 56/100 (grade C) and sits #367 of 497 on our board under the balanced default weighting.
- Semaglutide
- $199/mo (all doses, 12-month plan, compounded)
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Compounded only
- Oral option
- Yes
- Verification
- Not independently listed
Best for: Shoppers wanting all-inclusive compounded semaglutide with supplies included.
MatchScript's take: Our #367 pick of 497 — one of the few with a non-injection route, scored on the same six factors as everyone else.
The factor breakdown
SkyRx on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Semaglutide from $199/mo (all doses, 12-month plan, compounded) puts Budget Fit at a below-par 55 — above the budget tiers.
Limited or undisclosed state coverage can slow your start, for a below-par 53 on Speed to Start.
SkyRx adds an oral/sublingual route on top of injectables, for a below-par 64 on Formulary Match.
Support lands at a below-par 73 — lighter, meds-first support.
Flexibility scores a below-par 20 — fewer levers to flex your plan.
Disclosure here is thinner than the top of the board give a below-par 72 on Transparency.
Pricing in context
How SkyRx's monthly price sits against the category median and the cheapest provider we track.
What we like
- All-inclusive 199 dollars per month covers medication, supplies, doctor visit and shipping
- Offers both injectable and oral semaglutide, dispensed by FDA-registered 503B pharmacies
- Same-day shipping for orders before 2pm ET in temperature-controlled packaging
The caveats
- 199 dollars pricing requires a 12-month subscription paid upfront
- Tirzepatide only listed as coming soon
- GLP-1s not yet available in all 50 states; specific states not listed
Who it's for — and who should skip it
Choose SkyRx if shoppers wanting all-inclusive compounded semaglutide with supplies included.
Skip it if that doesn't sound like you. A closer fit may be EOS Health (Match Score 56) — or take the quiz to see where SkyRx lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
SkyRx against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | SkyRxthis provider | CoreAge Rxour #1 | EOS Healthclosest scorer |
|---|---|---|---|
| Sema price | $199/mo (all doses, 12-month plan, compounded) | $149/mo | $199/mo (compounded) |
| Coverage | Coverage not published | All 50 states | 40 states |
| Formulary | Injectable + oral | Injectable | Injectable |
| Match Score | 56 · C | 91 · A− | 56 · C |
SkyRx, answered
Is SkyRx legit?
SkyRx is a real, operating GLP-1 telehealth program, but we don't find it on the LegitScript registry, so it carries less third-party verification than the certified providers on our board. It dispenses compounded medication, which isn't FDA-approved. Vet the prescriber and pharmacy before you commit.
How much does SkyRx cost?
SkyRx lists compounded semaglutide from $199/mo (all doses, 12-month plan, compounded) — above our category median of $179/mo. These are the provider's public figures at our last review (July 2026); confirm on their site, since some teaser tiers step up after month one.
Does SkyRx ship to my state?
SkyRx operates in a limited set of states (Coverage not published). If yours isn't on that list, you'll need a nationwide provider instead.
SkyRx vs CoreAge Rx — which is better?
Both are on our board. SkyRx scores 56/100; CoreAge Rx leads our default ranking at 91/100 for its flat nationwide pricing on both molecules and easy cancellation. SkyRx can still win for you if its strengths match your priorities — best for: Shoppers wanting all-inclusive compounded semaglutide with supplies included. Run the quiz to see which comes out ahead for you.
Pricing & state data last verified July 2026 from SkyRx's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on SkyRx's site. Not medical advice; see our disclosure.
SkyRx earns a Match Score of 56/100 (grade C) and sits #367 of 497 on our board under the balanced default weighting. SkyRx (sky-rx.co) is a US telehealth weight-loss program offering compounded semaglutide as an injection or oral drops, with compounded tirzepatide listed as coming soon. Best for: Shoppers wanting all-inclusive compounded semaglutide with supplies included. If it isn't the right fit, EOS Health is a sensible alternative to weigh next.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest SkyRx on the board.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match88/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry on this board.88/100
- #3Match86/ 100HealthRXA LegitScript-certified, physician-supervised program with a rare oral GLP-1 tablet alongside injectables — both molecules, transparent no-insurance pricing, and a brand-name path.86/100
- #4Match86/ 100ShedRxA weight-focused program that also offers an oral/sublingual route for the needle-averse.86/100
- #5Match88/ 100Ondra HealthNear rock-bottom pricing on both molecules plus some brand access — a rare budget-and-breadth combo, nationwide.88/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| Strive Pharmacy#368 | 56 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Vital Edge#369 | 56 | $350/mo (compounded) | $450/mo (compounded) | Coverage not published | Alternatives | Visit |
| Vyora Wellness#370 | 56 | $299/mo (compounded) | $399/mo (compounded) | Coverage not published | Alternatives | Visit |
| Balanced Hormone Health#371 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Good Life Meds#372 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| HealthHub#373 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| HumeCare+#374 | 55 | $199/mo (starting dose, compounded) | Not disclosed | Coverage not published | Alternatives | Visit |
| Klarity Health#375 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Medi-Weightloss#376 | 55 | $199/mo (promotional rate, brand-name) | Not disclosed | Coverage not published | Alternatives | Visit |
| Meto#377 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Mevo Health#378 | 55 | $199/mo (all doses, compounded) | $259/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| Nu Image Medical#379 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| RedBox Rx#380 | 55 | $269/mo (all doses, 6-month plan, compounded) | $429/mo | Coverage not published | Alternatives | Visit |
| Reset Solutions#381 | 55 | Not disclosed | Not disclosed | 1 states | Alternatives | Visit |
| Tonik Wellness#382 | 55 | $225/mo (compounded) | $349/mo (compounded) | Coverage not published | Alternatives | Visit |
| UR Meds#383 | 55 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Valhalla Vitality#384 | 55 | $449/mo (compounded) | $449/mo (compounded) | Coverage not published | Alternatives | Visit |
| VivioMD#385 | 55 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Walgreens Weight Management#386 | 55 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Brello Health#387 | 54 | Not disclosed | Not disclosed | 35 states | Alternatives | Visit |
| ClickSlim#388 | 54 | Not disclosed | $349/mo (compounded) | Coverage not published | Alternatives | Visit |
| Dollar Dad Club#389 | 54 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| LifespanningRx#390 | 54 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Prime Health#391 | 54 | $299/mo (compounded) | $399/mo (compounded) | Coverage not published | Alternatives | Visit |