Framework review
Framework is a personalized-plan GLP-1 telehealth platform offering compounded semaglutide and tirzepatide with doctor-guided treatment selection.
- Scores never bought
- 537 providers tracked
- Every factor auditable
- Updated August 2026
Framework publishes no price before intake, which makes it hard to compare against programs that do — the biggest mark against it here.
- Semaglutide
- Not disclosed
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Compounded only
- Oral option
- Injectable only
- Verification
- Not independently listed
Best for: People who want aggressive $25/week pricing with a named 503B pharmacy partner.
MatchScript's take: Our #249 pick of 537 — a focused, straightforward program.
The factor breakdown
Framework on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Its lowest tier isn't clearly disclosed puts Budget Fit at a solid 84 — fair mid-market value.
Limited or undisclosed state coverage can slow your start, for a below-par 50 on Speed to Start.
Framework sticks to compounded injectables, for a below-par 66 on Formulary Match.
Support lands at a below-par 68 — lighter, meds-first support.
Flexibility scores a below-par 41 — fewer levers to flex your plan.
Thinner public disclosure than the top of the ranking keeps Transparency at a below-par 72.
Pricing in context
How Framework's monthly price sits against the category median and the cheapest provider we track.
What we like
- Named 503B pharmacy partner (The Pharmacy Hub) disclosed — the FDA-registered outsourcing-facility pathway, distinct from 503A
- Publishes the FDA compounded-medication disclaimer
- $25/week pricing (~$100/mo) is among the most aggressive in the directory
- $0 membership fees
- Phone support published, toll-free (888) 412-0666
The caveats
- No monthly medication price is published: the tirzepatide and semaglutide pages carry no price at all, and the homepage advertises a per-week figure for 'GLP-1s' generally rather than a rate for either drug
- The only drug-specific prices anywhere on the site sit on a legacy page — semaglutide at $349 per three months and tirzepatide at $549 per three months
- A '$75/month with 3-month package' figure is footnoted as a promotion for new GLP-1 users only
- Different landing pages advertise different per-week rates, $25 on one and $19 on another
- Compounded semaglutide and tirzepatide are not FDA-approved finished products
Who it's for — and who should skip it
Framework is for people who want aggressive $25/week pricing with a named 503B pharmacy partner.
Skip it if that doesn't sound like you. A closer fit may be SkinnyRx (Match Score 64) — or take the quiz to see where Framework lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
Framework against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | Frameworkthis provider | CoreAge Rxour #1 | SkinnyRxclosest scorer |
|---|---|---|---|
| Sema price | Not disclosed | $99/mo at every dose | $354/mo |
| Coverage | Coverage not published | All 50 states | 47 states + DC |
| Formulary | Injectable | Injectable | Injectable + oral |
| Match Score | 64 · C | 91 · A− | 64 · C |
Framework, answered
Is Framework legit?
Framework is a real, operating GLP-1 telehealth program. LegitScript certification is the third-party check worth asking for — look for the seal on their site and confirm your prescriber is US-licensed at intake. It doesn't publish whether it dispenses compounded or brand-name medication, so ask which one you're being prescribed.
How much does Framework cost?
Framework doesn't publish a clear compounded-semaglutide price up front. You'll typically see full pricing after the intake questionnaire. Get the all-in monthly number in writing before you pay.
Does Framework ship to my state?
Framework doesn't publish a full state list, so confirm your state is covered during intake before you pay.
Framework vs SkinnyRx — which should I pick?
They score within a few points of each other: Framework at 64/100 and SkinnyRx at 64/100, so neither wins on the headline number. Framework is the better fit for people who want aggressive $25/week pricing with a named 503B pharmacy partner. SkinnyRx suits shoppers who want a tablet as well as an injection on either molecule, and who read the term attached to an advertised rate before they read the number. Run the quiz and the weighting shifts to whichever of those matters more to you.
Pricing & state data last verified August 2026 from Framework's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Framework's site. Not medical advice; see our disclosure.
Framework publishes no price before intake, which makes it hard to compare against programs that do — the biggest mark against it here. Its best showing is on cost. Best suited to people who want aggressive $25/week pricing with a named 503B pharmacy partner. If that is not you, SkinnyRx is the closest thing to it here.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest Framework here.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match84/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry in this ranking.84/100
- #3Match83/ 100EdenA polished, high-disclosure compounded program with strong nationwide coverage and hands-on support.83/100
- #4Match85/ 100RoA heavyweight telehealth brand with brand-name access and a polished experience — but opaque compounded pricing.85/100
- #5Match85/ 100No BS RXThe highest Transparency score here, and it is not close: twenty-four prices on one public page and four dispensing pharmacies named with street addresses.85/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| GetRelief Rx#250 | 64 | $212/mo | $364/mo | Coverage not published | Alternatives | Visit |
| Tell Her Doc#251 | 64 | $269/mo (microdose tier, plus a separate fee, compounded) | Not disclosed | All 50 states | Alternatives | Visit |
| Arc-1#252 | 64 | $200/mo (0.5 mg dose, compounded) | $200/mo (2.5 mg dose, compounded) | Coverage not published | Alternatives | Visit |
| WePeptideRx#253 | 64 | $189/mo | $202/mo | Coverage not published | Alternatives | Visit |
| TelePeptide#254 | 64 | $199/mo (starting dose, annual plan, compounded oral) | $249/mo | Coverage not published | Alternatives | Visit |
| VitaFusions IV#255 | 64 | $149/mo (all doses, plus a separate fee, compounded) | $192/mo | Coverage not published | Alternatives | Visit |
| Roen Rx#256 FDA issued Roen Health, Inc. dba RoenRx a warning letter in June 2026. See FDA's warning-letter database. | 64 | $151/mo (3-month plan, plus a separate fee, compounded) | $456/mo | Coverage not published | Alternatives | Visit |
| Alinwell#257 | 64 | $249/mo (charged every 30 days; the advertised rate is a first-month price) | $299/mo (charged every 30 days; the advertised rate is a first-month price) | All 50 states | Alternatives | Visit |
| Boston Medical Group#258 | 63 | $325/mo | $253/mo | 7 states | Alternatives | Visit |
| WeightRx#259 | 63 | $250/mo (compounded) | $83/mo (term not published, compounded) | Coverage not published | Alternatives | Visit |
| HeliMeds#260 | 63 | $260/mo | $162/mo | Coverage not published | Alternatives | Visit |
| AZ Health#261 | 63 | $179/mo (all doses, compounded) | $249/mo | Coverage not published | Alternatives | Visit |
| NP2GO#262 | 63 | $183/mo | $283/mo | 40 states | Alternatives | Visit |
| Options Medical Weight Loss#263 | 63 | $271/mo | $379/mo | Coverage not published | Alternatives | Visit |
| Cielo#264 | 63 | $141/mo | $192/mo | Coverage not published | Alternatives | Visit |
| Eloria#265 | 63 | $299/mo | Not disclosed | Coverage not published | Alternatives | Visit |
| AskRx#266 | 63 | $349/mo (all doses, brand-name) | $299/mo (2.5 mg dose, brand-name) | All 50 states | Alternatives | Visit |
| BloomWell Rx#267 | 63 | $202/mo | $253/mo | Coverage not published | Alternatives | Visit |
| Society of You#268 | 63 | $279/mo (promotional rate, compounded) | $425/mo (compounded) | Coverage not published | Alternatives | Visit |
| ARSYNL Rx#269 | 63 | $233/mo (compounded) | $233/mo | Coverage not published | Alternatives | Visit |
| Levers Health#270 | 63 | $251/mo | $402/mo | Coverage not published | Alternatives | Visit |
| LifeRx.md#271 | 63 | $174/mo | $174/mo | All 50 states | Alternatives | Visit |
| Willow#272 | 63 | $299/mo (starting dose, compounded) | $399/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Avono Health#273 | 63 | $269/mo (compounded) | $349/mo (compounded) | Coverage not published | Alternatives | Visit |