Framework review
Framework is a personalized-plan GLP-1 telehealth platform offering compounded semaglutide and tirzepatide with doctor-guided treatment selection.
- Scores never bought
- 497 providers tracked
- Every factor auditable
- Updated July 2026
Framework earns a Match Score of 63/100 (grade C) and sits #238 of 497 on our board under the balanced default weighting.
- Semaglutide
- $100/mo (starting dose, compounded)
- Tirzepatide
- $100/mo (starting dose, compounded)
- Coverage
- Coverage not published
- Brand-name
- Compounded only
- Oral option
- Injectable only
- Verification
- Not independently listed
Best for: People who want aggressive $25/week pricing with a named 503B pharmacy partner.
MatchScript's take: Our #238 pick of 497 — priced at or below the category median, scored on the same six factors as everyone else.
The factor breakdown
Framework on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Semaglutide from $100/mo (starting dose, compounded) puts Budget Fit at a middling 78 — above the budget tiers.
Limited or undisclosed state coverage can slow your start, for a below-par 50 on Speed to Start.
Framework sticks to compounded injectables, for a below-par 66 on Formulary Match.
Support lands at a below-par 68 — lighter, meds-first support.
Flexibility scores a below-par 41 — fewer levers to flex your plan.
Disclosure here is thinner than the top of the board give a below-par 72 on Transparency.
Pricing in context
How Framework's monthly price sits against the category median and the cheapest provider we track.
What we like
- Named 503B pharmacy partner (The Pharmacy Hub) disclosed — the FDA-registered outsourcing-facility pathway, distinct from 503A
- Publishes the FDA compounded-medication disclaimer
- $25/week pricing (~$100/mo) is among the most aggressive in the directory
- $0 membership fees
- Phone support published, toll-free (888) 412-0666
The caveats
- LegitScript ID / certification not shown on the homepage
- States-served list not disclosed
- Medical director / clinical leadership not disclosed
- Corporate legal entity not disclosed (no footer copyright)
- Governing law / arbitration venue not stated
Who it's for — and who should skip it
Choose Framework if people who want aggressive $25/week pricing with a named 503B pharmacy partner.
Skip it if that doesn't sound like you. A closer fit may be Arc-1 (Match Score 63) — or take the quiz to see where Framework lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
Framework against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | Frameworkthis provider | CoreAge Rxour #1 | Arc-1closest scorer |
|---|---|---|---|
| Sema price | $100/mo (starting dose, compounded) | $149/mo | $200/mo (0.5 mg dose, compounded) |
| Coverage | Coverage not published | All 50 states | Coverage not published |
| Formulary | Injectable | Injectable | Injectable |
| Match Score | 63 · C | 91 · A− | 63 · C |
Framework, answered
Is Framework legit?
Framework is a real, operating GLP-1 telehealth program, but we don't find it on the LegitScript registry, so it carries less third-party verification than the certified providers on our board. It dispenses compounded medication, which isn't FDA-approved. Vet the prescriber and pharmacy before you commit.
How much does Framework cost?
Framework lists compounded semaglutide from $100/mo (starting dose, compounded) and tirzepatide from $100/mo (starting dose, compounded) — below our category median of $179/mo. These are the provider's public figures at our last review (June 2026); confirm on their site, since some teaser tiers step up after month one.
Does Framework ship to my state?
Framework operates in a limited set of states (Coverage not published). If yours isn't on that list, you'll need a nationwide provider instead.
Framework vs CoreAge Rx — which is better?
Both are on our board. Framework scores 63/100; CoreAge Rx leads our default ranking at 91/100 for its flat nationwide pricing on both molecules and easy cancellation. Framework can still win for you if its strengths match your priorities — best for: People who want aggressive $25/week pricing with a named 503B pharmacy partner. Run the quiz to see which comes out ahead for you.
Pricing & state data last verified June 2026 from Framework's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Framework's site. Not medical advice; see our disclosure.
Framework earns a Match Score of 63/100 (grade C) and sits #238 of 497 on our board under the balanced default weighting. Framework is a personalized-plan GLP-1 telehealth platform offering compounded semaglutide and tirzepatide with doctor-guided treatment selection. Best for: People who want aggressive $25/week pricing with a named 503B pharmacy partner. If it isn't the right fit, Arc-1 is a sensible alternative to weigh next.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest Framework on the board.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match88/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry on this board.88/100
- #3Match86/ 100HealthRXA LegitScript-certified, physician-supervised program with a rare oral GLP-1 tablet alongside injectables — both molecules, transparent no-insurance pricing, and a brand-name path.86/100
- #4Match86/ 100ShedRxA weight-focused program that also offers an oral/sublingual route for the needle-averse.86/100
- #5Match88/ 100Ondra HealthNear rock-bottom pricing on both molecules plus some brand access — a rare budget-and-breadth combo, nationwide.88/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| June Health#239 | 63 | $179/mo (starting dose, compounded) | $179/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| MyStart Health#240 | 63 | $299/mo (all doses, compounded) | $299/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| Neo Soma Healthcare#241 | 63 | $199/mo | $330/mo | Coverage not published | Alternatives | Visit |
| RxPepsDirect#242 | 63 | $64/mo (starting dose, plus a separate fee, compounded) | $84/mo (starting dose, plus a separate fee, compounded) | 28 states | Alternatives | Visit |
| Society of You#243 | 63 | $279/mo (promotional rate, compounded) | $425/mo (compounded) | Coverage not published | Alternatives | Visit |
| TeleClinic#244 | 63 | $199/mo (compounded) | $299/mo (compounded) | 47 states | Alternatives | Visit |
| WePeptideRx#245 | 63 | $249/mo (compounded) | $249/mo (compounded) | Coverage not published | Alternatives | Visit |
| Aquivia Health#246 | 62 | $149/mo | $179/mo | Coverage not published | Alternatives | Visit |
| ARSYNL Rx#247 | 62 | $233/mo (compounded) | $366/mo (compounded) | Coverage not published | Alternatives | Visit |
| CLYR Health#248 | 62 | $229/mo (compounded) | $249/mo (compounded) | Coverage not published | Alternatives | Visit |
| Emerge Weight Loss#249 | 62 | Not disclosed | $287/mo (2.5 mg dose, compounded) | Coverage not published | Alternatives | Visit |
| FormBlends#250 | 62 | $99/mo (compounded) | $349/mo (compounded) | Coverage not published | Alternatives | Visit |
| Freya Meds#251 | 62 | $297/mo (compounded) | $390/mo (compounded) | Coverage not published | Alternatives | Visit |
| Good Girl Rx#252 | 62 | $134/mo (starting dose, annual plan, compounded) | $235/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Levers Health#253 | 62 | $247/mo (1.25 mg dose, compounded) | $296/mo (5 mg dose, compounded) | Coverage not published | Alternatives | Visit |
| Liberty#254 | 62 | $199/mo (compounded) | $299/mo (compounded) | Coverage not published | Alternatives | Visit |
| LifeRx.md#255 | 62 | $200/mo | $275/mo | All 50 states | Alternatives | Visit |
| LunaRx#256 | 62 | $199/mo (starting dose, compounded) | Not disclosed | Coverage not published | Alternatives | Visit |
| Lyfe Rx#257 | 62 | $225/mo (compounded) | $299/mo (compounded) | Coverage not published | Alternatives | Visit |
| MediRX#258 | 62 | $149/mo (compounded) | $199/mo (compounded) | Coverage not published | Alternatives | Visit |
| Mint Medical Clinic#259 | 62 | $299/mo (compounded) | $299/mo (compounded) | 1 states | Alternatives | Visit |
| Nucore Health#260 | 62 | $299/mo (starting dose, compounded) | $199/mo (microdose tier, compounded) | Coverage not published | Alternatives | Visit |
| Onyx Weight Loss#261 | 62 | $228/mo (starting dose, compounded) | $280/mo (starting dose, compounded) | 8 states | Alternatives | Visit |
| PauseRX#262 | 62 | $199/mo | $249/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |