Synergy Rx review
A nationwide platform with round-the-clock support that prints a starting figure on every product card and never says what it commits you to.
- Scores never bought
- 537 providers tracked
- Every factor auditable
- Updated August 2026
Synergy Rx scores where it does because of what it will not tell you.
- Semaglutide
- $249/mo
- Tirzepatide
- $399/mo
- Coverage
- All 50 states
- Brand-name
- Compounded only
- Oral option
- Yes
- Verification
- LegitScript-certified
Best for: People who value 24/7 access to a care team and want to see a number before starting an intake, even an incomplete one.
MatchScript's take: Publishes prices for its longevity injections and none at all for the GLP-1 it is listed here for.
The factor breakdown
Synergy Rx on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
There is no GLP-1 price to score. A provider that publishes nothing you can compare before an intake cannot be credited with value it has not demonstrated, so Budget Fit is 60.
Confirmed all-50-state access means it can usually prescribe within days, for a strong 88 on Speed to Start.
Synergy Rx adds an oral/sublingual route on top of injectables, for a below-par 70 on Formulary Match.
Support lands at a middling 78 — lighter, meds-first support.
Flexibility scores a below-par 70 — fewer levers to flex your plan.
No GLP-1 price on the public site, no published state list, and mandatory arbitration with a class-action waiver give a 58 — the lowest Transparency score in this ranking.
Pricing in context
How Synergy Rx's monthly price sits against the category median and the cheapest provider we track.
What we like
- Available in all 50 states, subject to state telehealth rules
- Unlimited 24/7 access to a care team, with unlimited appointments and messaging included
- LegitScript-certified, running on a named clinician network with four named 503A pharmacies
- Prices its longevity catalog openly, so the opacity is specific to weight loss rather than universal
The caveats
- Publishes no GLP-1 price anywhere on its public site — you cannot compare it on cost before committing to an intake
- Its full active-state list is not published; you have to contact support for it
- Mandatory individual arbitration with a class-action waiver, non-refundable consultation fees, and all prescription sales final
- Shares a clinician network and pharmacies with Breeze Meds and Care Bare Rx, and its correct domain is synergyrx.co — synergyrx.com is an unrelated parked domain
Who it's for — and who should skip it
Synergy Rx is for people who value 24/7 access to a care team and want to see a number before starting an intake, even an incomplete one.
Skip it if that doesn't sound like you. A closer fit may be RxSpan MD (Match Score 70) — or take the quiz to see where Synergy Rx lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
Synergy Rx against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | Synergy Rxthis provider | CoreAge Rxour #1 | Wholesome Clinicclosest scorer |
|---|---|---|---|
| Sema price | $249/mo | $99/mo at every dose | $233/mo |
| Coverage | All 50 states | All 50 states | 7 states |
| Formulary | Injectable + oral | Injectable | Injectable + oral + brand |
| Match Score | 68 · C | 91 · A− | 68 · C |
Synergy Rx, answered
Is Synergy Rx legit?
Yes — Synergy Rx is LegitScript-certified, a third-party check that a telehealth pharmacy operates within the rules. Like most programs here it dispenses compounded GLP-1s, which are made by a licensed pharmacy but aren't FDA-approved; confirm your prescriber is US-licensed at intake.
How much does Synergy Rx cost?
Synergy Rx lists compounded semaglutide from $249/mo and tirzepatide from $399/mo — above our category median of $199/mo. These are the provider's public figures at our last review (August 2026); confirm on their site, since some teaser tiers step up after month one.
Does Synergy Rx ship to my state?
Yes — Synergy Rx reports availability in all 50 states, so most people can start within days.
Synergy Rx vs RxSpan MD — which should I pick?
They score within a few points of each other: Synergy Rx at 68/100 and RxSpan MD at 70/100, so neither wins on the headline number. Synergy Rx is the better fit for people who value 24/7 access to a care team and want to see a number before starting an intake, even an incomplete one. RxSpan MD suits readers who want the pharmacy and the prescriber named up front and both a needle-free and a brand-name lane on the same account, and who will switch the plan selector back to Monthly themselves. Run the quiz and the weighting shifts to whichever of those matters more to you.
Pricing & state data last verified August 2026 from Synergy Rx's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Synergy Rx's site. Not medical advice; see our disclosure.
Synergy Rx scores where it does because of what it will not tell you. It reaches all 50 states, includes unlimited 24/7 access to a care team, is LegitScript-certified, and runs on a named clinician network with four named 503A pharmacies — and it prices its longevity catalog openly, so the opacity is specific to weight loss rather than universal. But it publishes no GLP-1 price anywhere on its public site: the Weight Loss category renders no priced products at all, and the cost FAQ says only that pricing varies by treatment plan and medication. Its full active-state list requires contacting support, consultation fees are non-refundable, all prescription sales are final, and disputes go to individual arbitration with a class-action waiver. It also shares a clinician network with Breeze Meds and Care Bare Rx. If you cannot compare it on cost before committing to an intake, we cannot rank it as though you could.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest Synergy Rx here.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match84/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry in this ranking.84/100
- #3Match83/ 100EdenA polished, high-disclosure compounded program with strong nationwide coverage and hands-on support.83/100
- #4Match85/ 100RoA heavyweight telehealth brand with brand-name access and a polished experience — but opaque compounded pricing.85/100
- #5Match85/ 100No BS RXThe highest Transparency score here, and it is not close: twenty-four prices on one public page and four dispensing pharmacies named with street addresses.85/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| Nolu#118 | 70 | $249 per 4 weeks | $336/mo | All 50 states plus Washington, D.C. | Alternatives | Visit |
| Fitness RX#119 | 70 | $192/mo | $303/mo | Coverage not published | Alternatives | Visit |
| PlexusDx#120 | 70 | $192/mo | $293/mo | All 50 states | Alternatives | Visit |
| ZYP Medical#121 | 70 | $152/mo | $236/mo | 6 states | Alternatives | Visit |
| Revel Health#122 | 70 | $202/mo | $253/mo | 45 states | Alternatives | Visit |
| Apex MD#123 | 70 | $299/mo | $399/mo | All 50 states | Alternatives | Visit |
| BiltRx#124 | 70 | $81/mo | $129/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| Hers#125 FDA issued Hims & Hers Health, Inc. dba Hers a warning letter in September 2025. See FDA's warning-letter database. | 70 | $199/mo (starting dose, compounded) | $299/mo (starting dose, plus a separate fee, brand-name) | All 50 states | Alternatives | Visit |
| Peak Wellness#126 | 70 | $253/mo | $354/mo | All 50 states | Alternatives | Visit |
| PlushCare#127 | 70 | $149/mo (starting dose, compounded) | $399/mo (starting dose, compounded) | All 50 states | Alternatives | Visit |
| Get Thin MD#128 | 70 | $199/mo (compounded) | $299/mo (compounded) | All 50 states | Alternatives | Visit |
| RestorLife Med#129 | 70 | $303/mo | $405/mo | All 50 states | Alternatives | Visit |
| TrueMe#130 | 70 | $141/mo | $151/mo | 6 states | Alternatives | Visit |
| TeleClinic#131 | 70 | $199/mo (standing rate) | $299/mo (standing rate) | 47 states | Alternatives | Visit |
| AHBARx#132 | 70 | $249/mo (consult and shipping included) | $349/mo (consult and shipping included) | All 50 states | Alternatives | Visit |
| Longevixx#133 | 70 | $199/mo (charged every 30 days) | $299/mo (charged every 30 days) | All 50 states | Alternatives | Visit |
| SexyMD#134 | 70 | $269 per 4 weeks (the advertised headline is a 48-week commitment rate) | $369 per 4 weeks (the advertised headline is a 48-week commitment rate) | 47 states | Alternatives | Visit |
| Kin Meds#135 FDA issued Kin Meds a warning letter in February 2026. See FDA's warning-letter database. | 69 | $202/mo | $253/mo | Coverage not published | Alternatives | Visit |
| Ozari Health#136 | 69 | $178/mo | $238/mo | All 50 states | Alternatives | Visit |
| Bodi Envi#137 | 69 | $157/mo | $232/mo | Coverage not published | Alternatives | Visit |
| GobyMeds#138 | 69 | $169/mo (all doses, compounded) | $145/mo | Coverage not published | Alternatives | Visit |
| MyFastRx#139 | 69 | $139/mo | $199/mo | All 50 states | Alternatives | Visit |
| Recovery Delivered#140 | 69 | $203/mo | $223/mo | 32 states | Alternatives | Visit |
| Trillium Meds#141 | 69 | $159/mo | $249/mo | All 50 states | Alternatives | Visit |
Synergy Rx is ranked on our best semaglutide providers, best tirzepatide providers, best GLP-1 programs and best oral GLP-1 providers boards, scored on the same six factors as every other provider there.