Rylo Health review: price, pros & cons
Rylo Health sells compounded semaglutide at $139 a month and tirzepatide at $229 month-to-month — the same at every dose, with no membership fee — and names its pharmacy and physician group.
- Scores never bought
- 599 providers tracked
- Every factor auditable
Rylo Health sells compounded semaglutide and tirzepatide as weekly injections at one price that does not change as your dose rises.
- Semaglutide
- $139/mo
- Tirzepatide
- $229/mo
- Coverage
- All 50 states
- Brand-name
- Not listed
- Oral option
- Not listed
- Verification
- Not independently listed
Best for: People who want a flat monthly price that will not rise as the dose goes up, a named pharmacy, and one-click cancellation.
MatchScript's take: Flat, dose-independent pricing with a named pharmacy and painless cancellation — a tidy package for a weekly injection.
The factor breakdown
Rylo Health on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Month-to-month semaglutide is $139 at every dose, with no membership on top.
Published all-50-state access broadens availability; appointment and shipping times still need confirmation, for a solid 84 on Speed to Start.
Rylo Health does not have a confirmed oral or brand-name option in our comparison, for a below-par 72 on Formulary Match.
Support Level scores 76/100 in our comparison. Confirm who answers clinical questions, how to reach them and whether follow-up visits cost extra.
No contract and one-button cancellation, though the cheaper rates bill three months at a time.
Monthly and quarterly prices, the dispensing pharmacy's address and the prescribing physician group are all published.
Pricing in context
How Rylo Health's monthly price sits against the category median and the cheapest provider we track.
| Monthly price | Semaglutide | Tirzepatide |
|---|---|---|
| Rylo Healththis providerVisit | $139/mo−$51 vs median | $229/mo−$30 vs median |
| Category median240 tracked | $190/mo | $259/mo |
| Cheapest trackedMondaeVisit | $87/mo | $126/mo |
For a fair comparison, check the full cost of semaglutide or tirzepatide, including care fees, dose changes and the amount due at each renewal.
What we found on their site
Read on Rylo Health's own website in October 2026. Quoted text is theirs.
- With the Monthly option selected, the tirzepatide page shows "$229 a month", "Save $832 with quarterly" and "Same price at every dose. No contract, cancel any month."
- The homepage FAQ says "Prescriptions are filled by VialsRX, 6220 Westpark Dr, Houston, TX 77057" and that clinical care is provided by Lone Star Virtual Health PLLC.
- Its cancellation section reads "One button cancels your membership and you get a confirmation email."
What we like
- Flat month-to-month pricing at every dose: semaglutide $139 and tirzepatide $229, or $100 and $160 a month billed quarterly
- Names its pharmacy, VialsRX in Houston, with address and phone number, and its clinical group, Lone Star Virtual Health
- Cancel any time with one button, with no retention call and no cancellation fee
- Free two-day cold-packed shipping, syringes and supplies included, and a care team you can text
- Nothing to pay to start, and fully refundable before your first physician consultation
The caveats
- Product pages open on the quarterly price ($100 or $160), so the month-to-month rate is only visible after switching the toggle
- Injections only — there is no needle-free GLP-1 and no brand-name Wegovy or Zepbound
- Compounded semaglutide and tirzepatide are not FDA-approved
- Some formulations and fulfillment options vary by state
- The lowest rates require paying for three months at a time ($299 or $479 per quarter)
Rylo Health · semaglutide $139/mo · tirzepatide $229/moCheck the current price and eligibility on their site.
Visit Rylo HealthWho it's for — and who should skip it
Rylo Health is for people who want a flat monthly price that will not rise as the dose goes up, a named pharmacy, and one-click cancellation.
Skip it if that doesn't sound like you. A closer fit may be Strut Health (Match Score 79) — or take the quiz to see where Rylo Health lands for your priorities.
Before you choose care
What semaglutide costs. Compare medication costs, ongoing fees and prepaid plans before choosing care.
What tirzepatide costs. See how dose, medication type and billing terms affect the total price.
Compounded vs. brand-name GLP-1s. Learn how approval, evidence and pharmacy oversight differ between these options.
How to choose a provider. Compare clinical support, pharmacy transparency and cancellation terms alongside price.
How it compares to CoreAge Rx & the closest scorer
Rylo Health against CoreAge Rx and the provider that scores closest to it. Green marks the row leader.
| How it compares | Rylo Healththis provider | CoreAge Rxfeatured | Strut Healthclosest scorer |
|---|---|---|---|
| Sema price | $139/mo | $99/mo at every dose | $129/mo |
| Coverage | All 50 states | U.S. only — restrictions vary by state and therapy, list not published | 49 states — Arkansas excluded |
| Formulary | Injectable | Injectable | Injectable + oral |
| Match Score | 79 · C | 91 · A− | 79 · C |
Rylo Health, answered
Is Rylo Health legit?
Rylo Health is a real, operating GLP-1 telehealth program. LegitScript certification is the third-party check worth asking for — look for the seal on their site and confirm your prescriber is US-licensed at intake. Like most programs here it dispenses compounded GLP-1s, which are made by a licensed pharmacy but aren't FDA-approved.
How much does Rylo Health cost?
Rylo Health lists compounded semaglutide from $139/mo and tirzepatide from $229/mo — below our category median of $190/mo. These are the provider's public figures at our last review; confirm on their site, since some teaser tiers step up after month one.
Does Rylo Health ship to my state?
Yes — Rylo Health reports availability in all 50 states, so most people can start within days.
Rylo Health vs CoreAge Rx — which is better?
Rylo Health scores 79/100 and CoreAge Rx scores 91/100, the latter on the strength of the same flat price at every dose on both molecules and easy cancellation. Rylo Health can still win for you if its strengths match your priorities: it is built for people who want a flat monthly price that will not rise as the dose goes up, a named pharmacy, and one-click cancellation. Run the quiz to see which comes out ahead for you.
Pricing & state data come from Rylo Health's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Rylo Health's site. Not medical advice; see our disclosure.
Rylo Health sells compounded semaglutide and tirzepatide as weekly injections at one price that does not change as your dose rises. Month to month, semaglutide is $139 and tirzepatide $229; paying quarterly brings that to $100 and $160 a month. The price covers the physician review, medication, syringes and free two-day cold-packed shipping, with no membership fee. Rylo names its pharmacy, VialsRX in Houston, and the physician group that prescribes, and it lets you cancel with one button. Nothing is charged until you are reviewed, and you can get a refund before the first consultation. The downsides: the product pages open on the quarterly price, there is no needle-free or brand-name option, and compounded medications are not FDA-approved. Bottom line: one of the clearer flat-price injection services for someone who wants to cancel easily.
Compare with other providers
Five more providers to compare (providers we have a commercial relationship with are listed first), then the 24 programs that sit nearest Rylo Health here.
- Match91/ 100CoreAge RxCompounded semaglutide at $99 and tirzepatide at $149 a month, the same price at every dose, with no membership fee and a full refund if the doctor doesn't approve you.91/100
- Match86/ 100EdenCompounded semaglutide at $99 and tirzepatide at $129 a month at every dose, with care, coaching and shipping included, a brand-name Wegovy option, and medication from Eden's own pharmacy network.86/100
- Match81/ 100yourEraA personalized-health brand selling compounded semaglutide and tirzepatide alongside NAD+, sermorelin and microdosing protocols, with an optional coaching-and-labs bundle, nationwide.81/100
- Match80/ 100HealthRXA LegitScript-certified program selling compounded semaglutide and tirzepatide on one flat plan price — consult, medication and overnight shipping included — with a full refund if a provider doesn't approve you.80/100
- Match80/ 100ShedRxCompounded semaglutide and tirzepatide as injections, oral drops or lozenges, plus brand-name Wegovy, Zepbound and the Foundayo pill — month to month or cheaper on longer plans.80/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| Ivologist | 79 | $199/mo | $299/mo | All 50 states | Alternatives | Visit |
| Healthicare | 79 | $126/mo | $144/mo | All 50 states (California priced separately) | Alternatives | Visit |
| Luvo Health | 76 | $226/mo | $270/mo | All 50 states | Alternatives | Visit |
| EverSlim | 78 | $113/mo | $136/mo | All 50 states | Alternatives | Visit |
| Idgie Health | 78 | $149/mo | $229/mo | All 50 states | Alternatives | Visit |
| MadeMed | 75 | $239/mo (quarterly plan) | $399/mo (quarterly plan) | Varies by product (23 states for injectable semaglutide, 40 for oral) | Alternatives | Visit |
| Trimi | 77 | $175/mo | $235/mo | All 50 states | Alternatives | Visit |
| Belle Health | 77 | $199/mo | $249/mo | All 50 states | Alternatives | Visit |
| Amazon One Medical | 77 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Bionomy Health | 77 | $189/mo | $249/mo | 48 states (not Alaska or Hawaii) | Alternatives | Visit |
| PlexusDx | 77 | $189/mo | $289/mo | All 50 states | Alternatives | Visit |
| NextMeds | 77 | $79/mo | $109/mo | All 50 states | Alternatives | Visit |
| Zappy Health | 77 | $249/mo | $349/mo | 49 states — all except Hawaii | Alternatives | Visit |
| Bodi Envi | 77 | $155/mo | $229/mo | All 50 states | Alternatives | Visit |
| Measured | 77 | $199/mo | $299/mo | 26 states | Alternatives | Visit |
| OurView Health | 77 | $109/mo | $129/mo | 46 states + DC (not AR, CT, HI or NJ) | Alternatives | Visit |
| NexLife | 77 | $139/mo | $169/mo | All 50 states | Alternatives | Visit |
| PepHaūs | 77 | $169/mo | $239/mo | All 50 states plus Washington, D.C. | Alternatives | Visit |
| Rixa Health | 77 | $140/mo (oral, starting dose) | $225/mo (oral, starting dose) | Most states; Alaska, Arkansas, Hawaii, North Dakota and South Dakota listed as forthcoming | Alternatives | Visit |
| Renlo Health | 77 | $199/mo | $269/mo | All 50 states + DC | Alternatives | Visit |
| Oak | 74 | $190/mo | Not disclosed | All 50 states | Alternatives | Visit |
| Wellorithm | 74 | Not disclosed | Not disclosed | All 50 states plus Washington, D.C. | Alternatives | Visit |
| SnagRx | 74 | $99/mo | $149/mo | All 50 states plus Washington D.C. (per Terms) | Alternatives | Visit |
| Effecty | 76 | $170/mo | $235/mo | All 50 states | Alternatives | Visit |
Rylo Health appears on our best semaglutide providers, best tirzepatide providers and best GLP-1 programs boards, scored on the same six factors as every other provider there.