PlexusDx review
PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states.
- Scores never bought
- 497 providers tracked
- Every factor auditable
- Updated July 2026
PlexusDx earns a Match Score of 73/100 (grade C) and sits #79 of 497 on our board under the balanced default weighting.
- Semaglutide
- $149/mo (starting dose, compounded)
- Tirzepatide
- $249/mo (starting dose, compounded)
- Coverage
- All 50 states
- Brand-name
- Compounded only
- Oral option
- Injectable only
- Verification
- Not independently listed
Best for: Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization.
MatchScript's take: Our #79 pick of 497 — priced at or below the category median, scored on the same six factors as everyone else.
The factor breakdown
PlexusDx on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Semaglutide from $149/mo (starting dose, compounded) puts Budget Fit at a below-par 72 — above the budget tiers.
Confirmed all-50-state access means it can usually prescribe within days, for a solid 86 on Speed to Start.
PlexusDx sticks to compounded injectables, for a below-par 72 on Formulary Match.
Support lands at a below-par 66 — lighter, meds-first support.
Flexibility scores a below-par 55 — fewer levers to flex your plan.
Disclosure here is thinner than the top of the board give a strong 90 on Transparency.
Pricing in context
How PlexusDx's monthly price sits against the category median and the cheapest provider we track.
What we like
- Licensed providers available in all 50 states
- Range of options including low-cost microdose GLP-1 from $129/mo
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
- Compounded medications from state-licensed pharmacies
The caveats
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
- Genetic-panel upsell may not add clinical value for everyone
- Tirzepatide pricing from $249/mo is higher than budget rivals
- No insurance accepted
Who it's for — and who should skip it
Choose PlexusDx if shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization.
Skip it if that doesn't sound like you. A closer fit may be System Labs (Match Score 76) — or take the quiz to see where PlexusDx lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
PlexusDx against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | PlexusDxthis provider | CoreAge Rxour #1 | FitRxclosest scorer |
|---|---|---|---|
| Sema price | $149/mo (starting dose, compounded) | $149/mo | $151/mo (quarterly plan, compounded) |
| Coverage | All 50 states | All 50 states | All 50 states |
| Formulary | Injectable | Injectable | Injectable + brand |
| Match Score | 73 · C | 91 · A− | 73 · C |
PlexusDx, answered
Is PlexusDx legit?
PlexusDx is a real, operating GLP-1 telehealth program, but we don't find it on the LegitScript registry, so it carries less third-party verification than the certified providers on our board. It dispenses compounded medication, which isn't FDA-approved. Vet the prescriber and pharmacy before you commit.
How much does PlexusDx cost?
PlexusDx lists compounded semaglutide from $149/mo (starting dose, compounded) and tirzepatide from $249/mo (starting dose, compounded) — below our category median of $179/mo. These are the provider's public figures at our last review (July 2026); confirm on their site, since some teaser tiers step up after month one.
Does PlexusDx ship to my state?
Yes — PlexusDx reports availability in all 50 states, so most people can start within days.
PlexusDx vs CoreAge Rx — which is better?
Both are on our board. PlexusDx scores 73/100; CoreAge Rx leads our default ranking at 91/100 for its flat nationwide pricing on both molecules and easy cancellation. PlexusDx can still win for you if its strengths match your priorities — best for: Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization. Run the quiz to see which comes out ahead for you.
Pricing & state data last verified July 2026 from PlexusDx's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on PlexusDx's site. Not medical advice; see our disclosure.
PlexusDx earns a Match Score of 73/100 (grade C) and sits #79 of 497 on our board under the balanced default weighting. PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states. Best for: Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization. If it isn't the right fit, System Labs is a sensible alternative to weigh next.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest PlexusDx on the board.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match88/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry on this board.88/100
- #3Match86/ 100HealthRXA LegitScript-certified, physician-supervised program with a rare oral GLP-1 tablet alongside injectables — both molecules, transparent no-insurance pricing, and a brand-name path.86/100
- #4Match86/ 100ShedRxA weight-focused program that also offers an oral/sublingual route for the needle-averse.86/100
- #5Match88/ 100Ondra HealthNear rock-bottom pricing on both molecules plus some brand access — a rare budget-and-breadth combo, nationwide.88/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| Queen RX#80 | 73 | $100/mo (quarterly plan, compounded) | Not disclosed | 45 states | Alternatives | Visit |
| Rebody Health#81 | 73 | $200/mo (starting dose, compounded) | $250/mo (starting dose, compounded) | 47 states | Alternatives | Visit |
| Wholesome Clinic#82 | 73 | $149/mo (starting dose, compounded) | $349/mo (starting dose, compounded) | 7 states | Alternatives | Visit |
| Wisp#83 | 73 | $225/mo (compounded oral) | $99/mo (starting dose, brand-name) | Coverage not published | Alternatives | Visit |
| ZYP Medical#84 | 73 | $150/mo | $233/mo | 6 states | Alternatives | Visit |
| Synergy Rx#85 | 70 | $199/mo (starting at, terms undisclosed) | $349/mo (starting at, terms undisclosed) | All 50 states | Alternatives | Visit |
| Amble#86 | 72 | $179/mo (starting dose, compounded) | $289/mo (starting dose, compounded) | All 50 states | Alternatives | Visit |
| Candor Rx#87 | 72 | $99/mo (all doses, compounded) | $149/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| Care Clinics#88 | 72 | $148/mo (compounded) | $329/mo (compounded) | 32 states | Alternatives | Visit |
| Kin Meds#89 | 72 | $149/mo (brand Wegovy) | $149/mo (brand Zepbound) | Coverage not published | Alternatives | Visit |
| Measured#90 | 72 | $119/mo (compounded) | $229/mo (compounded) | Coverage not published | Alternatives | Visit |
| NextMeds#91 | 72 | $129/mo (plus a separate fee, compounded) | $179/mo (plus a separate fee, compounded) | All 50 states | Alternatives | Visit |
| NiceRx#92 | 72 | $199/mo (compounded) | $299/mo (compounded) | 46 states | Alternatives | Visit |
| NuvaHealth#93 | 72 | $139/mo (first-month rate, compounded) | $229/mo (first-month rate, compounded) | Coverage not published | Alternatives | Visit |
| Revel Health#94 | 72 | $199/mo (compounded) | $249/mo (starting dose, compounded) | 45 states | Alternatives | Visit |
| Rylo Health#95 | 72 | $149/mo (promotional rate, compounded) | $249/mo (compounded) | All 50 states | Alternatives | Visit |
| TRYM Health#96 | 72 | $96/mo (all doses, compounded) | $126/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| Vytora Health#97 | 72 | $180/mo (all doses, compounded) | $249/mo (all doses, compounded) | All 50 states | Alternatives | Visit |
| Zappy Health#98 | 72 | $159/mo (compounded) | $299/mo (compounded) | 42 states | Alternatives | Visit |
| 24hrDOC#99 | 71 | $149/mo (2 mg dose, compounded) | $239/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Apex MD#100 | 71 | $299/mo | $399/mo | All 50 states | Alternatives | Visit |
| BiltRx#101 | 71 | $125/mo (all doses, compounded) | $129/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| Bodi Envi#102 | 71 | $179/mo | $249/mo | Coverage not published | Alternatives | Visit |
| Boston Medical Group#103 | 71 | $66/mo (starting dose, compounded) | Not disclosed | 7 states | Alternatives | Visit |