Ryze Rx review
Ryze Rx is a prescription telehealth platform for weight loss, TRT and peptide therapy, prescribing through board-certified physicians and shipping from US-licensed compounding pharmacies.
- Scores never bought
- 497 providers tracked
- Every factor auditable
- Updated July 2026
Ryze Rx earns a Match Score of 59/100 (grade C) and sits #320 of 497 on our board under the balanced default weighting.
- Semaglutide
- $199/mo (starting dose, 3 month plan, compounded)
- Tirzepatide
- $199/mo (starting dose, 3 month plan, compounded)
- Coverage
- Coverage not published
- Brand-name
- Compounded only
- Oral option
- Injectable only
- Verification
- Not independently listed
Best for: People who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.
MatchScript's take: Our #320 pick of 497 — a focused, straightforward program, scored on the same six factors as everyone else.
The factor breakdown
Ryze Rx on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Semaglutide from $199/mo (starting dose, 3 month plan, compounded) puts Budget Fit at a below-par 43 — above the budget tiers.
Limited or undisclosed state coverage can slow your start, for a below-par 67 on Speed to Start.
Ryze Rx sticks to compounded injectables, for a below-par 66 on Formulary Match.
Support lands at a below-par 68 — lighter, meds-first support.
Flexibility scores a below-par 41 — fewer levers to flex your plan.
Disclosure here is thinner than the top of the board give a below-par 72 on Transparency.
Pricing in context
How Ryze Rx's monthly price sits against the category median and the cheapest provider we track.
What we like
- Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
- Physician consultation, ongoing clinical support and discreet shipping included with each prescription
- Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)
- Free shipping, 24hr prescription turnaround, FSA/HSA eligible; care advertised in all 50 states
The caveats
- Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
- Pharmacy partners not named - only 'US-licensed compounding pharmacies'
- Homepage advertises GLP-1s 'from $149/mo' but the catalog lists $199/mo
- On-site '4.9/5, 2,400+ reviews' is self-reported, not an independently verified rating
Who it's for — and who should skip it
Choose Ryze Rx if people who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.
Skip it if that doesn't sound like you. A closer fit may be Alegro Health (Match Score 59) — or take the quiz to see where Ryze Rx lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
Ryze Rx against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | Ryze Rxthis provider | CoreAge Rxour #1 | Alegro Healthclosest scorer |
|---|---|---|---|
| Sema price | $199/mo (starting dose, 3 month plan, compounded) | $149/mo | $199/mo (starting dose, compounded) |
| Coverage | Coverage not published | All 50 states | Coverage not published |
| Formulary | Injectable | Injectable | Injectable |
| Match Score | 59 · C | 91 · A− | 59 · C |
Ryze Rx, answered
Is Ryze Rx legit?
Ryze Rx is a real, operating GLP-1 telehealth program, but we don't find it on the LegitScript registry, so it carries less third-party verification than the certified providers on our board. It dispenses compounded medication, which isn't FDA-approved. Vet the prescriber and pharmacy before you commit.
How much does Ryze Rx cost?
Ryze Rx lists compounded semaglutide from $199/mo (starting dose, 3 month plan, compounded) and tirzepatide from $199/mo (starting dose, 3 month plan, compounded) — above our category median of $179/mo. These are the provider's public figures at our last review (June 2026); confirm on their site, since some teaser tiers step up after month one.
Does Ryze Rx ship to my state?
Ryze Rx operates in a limited set of states (Coverage not published). If yours isn't on that list, you'll need a nationwide provider instead.
Ryze Rx vs CoreAge Rx — which is better?
Both are on our board. Ryze Rx scores 59/100; CoreAge Rx leads our default ranking at 91/100 for its flat nationwide pricing on both molecules and easy cancellation. Ryze Rx can still win for you if its strengths match your priorities — best for: People who want compounded GLP-1s plus a broad TRT and peptide menu on one platform. Run the quiz to see which comes out ahead for you.
Pricing & state data last verified June 2026 from Ryze Rx's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Ryze Rx's site. Not medical advice; see our disclosure.
Ryze Rx earns a Match Score of 59/100 (grade C) and sits #320 of 497 on our board under the balanced default weighting. Ryze Rx is a prescription telehealth platform for weight loss, TRT and peptide therapy, prescribing through board-certified physicians and shipping from US-licensed compounding pharmacies. Best for: People who want compounded GLP-1s plus a broad TRT and peptide menu on one platform. If it isn't the right fit, Alegro Health is a sensible alternative to weigh next.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest Ryze Rx on the board.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match88/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry on this board.88/100
- #3Match86/ 100HealthRXA LegitScript-certified, physician-supervised program with a rare oral GLP-1 tablet alongside injectables — both molecules, transparent no-insurance pricing, and a brand-name path.86/100
- #4Match86/ 100ShedRxA weight-focused program that also offers an oral/sublingual route for the needle-averse.86/100
- #5Match88/ 100Ondra HealthNear rock-bottom pricing on both molecules plus some brand access — a rare budget-and-breadth combo, nationwide.88/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| Shapely#321 | 59 | Not disclosed | Not disclosed | 4 states | Alternatives | Visit |
| Teleios Health#322 | 59 | $99/mo (starting dose, compounded) | $139/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Trinity Meds#323 | 59 | $149/mo (compounded) | $199/mo (compounded) | Coverage not published | Alternatives | Visit |
| Ascend Medical#324 | 58 | Not disclosed | Not disclosed | 2 states | Alternatives | Visit |
| CaliberRx#325 | 58 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| DreamHug Medical#326 | 58 | $188/mo (starting dose, compounded) | $238/mo (starting dose, compounded) | All 50 states | Alternatives | Visit |
| Evernow#327 | 58 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Florida Weight Loss MD#328 | 58 | Not disclosed | Not disclosed | 1 states | Alternatives | Visit |
| Joey Med#329 | 58 | $279/mo (compounded) | $399/mo (compounded) | All 50 states | Alternatives | Visit |
| LifeMD#330 | 58 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Lumora#331 | 58 | $199/mo (starting dose, plus a separate fee, compounded) | $299/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Mojoon#332 | 58 | $450/mo (starting dose, compounded) | Not disclosed | Coverage not published | Alternatives | Visit |
| Next Vial#333 | 58 | $250/mo (compounded) | Not disclosed | 49 states | Alternatives | Visit |
| Novi#334 | 58 | $174/mo (starting dose, compounded) | $283/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| NowPatient#335 | 58 | $1,349/mo (brand Wegovy) | $1,069/mo (brand Mounjaro, promotional rate) | Coverage not published | Alternatives | Visit |
| Obu Health#336 | 58 | $190/mo (starting dose, plus a separate fee, compounded) | $239/mo (starting dose, plus a separate fee, compounded) | Coverage not published | Alternatives | Visit |
| Somira Health#337 | 58 | $190/mo (compounded) | $285/mo (compounded) | Coverage not published | Alternatives | Visit |
| TD Tele-Doc Weight Loss#338 | 58 | Not disclosed | Not disclosed | 2 states | Alternatives | Visit |
| Unique Physique#339 | 58 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Bioverse#340 | 57 | $129/mo (starting dose, compounded) | $399/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| BodyLogicMD#341 | 57 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Call-On-Doc#342 | 57 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Elevated Health#343 | 57 | $296/mo (compounded) | $359/mo (compounded) | Coverage not published | Alternatives | Visit |
| Empower Pharmacy#344 | 57 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |