Ryze Rx review
Ryze Rx is a prescription telehealth platform for weight loss, TRT and peptide therapy, prescribing through board-certified physicians and shipping from US-licensed compounding pharmacies.
- Scores never bought
- 537 providers tracked
- Every factor auditable
- Updated August 2026
Semaglutide here is $199/mo (starting dose, 3 month plan, compounded) — almost exactly our category median of $199.
- Semaglutide
- $199/mo (starting dose, 3 month plan, compounded)
- Tirzepatide
- $166/mo
- Coverage
- Coverage not published
- Brand-name
- Compounded only
- Oral option
- Injectable only
- Verification
- Not independently listed
Best for: People who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.
MatchScript's take: Our #327 pick of 537 — priced at or below the category median.
The factor breakdown
Ryze Rx on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.
Semaglutide from $199/mo (starting dose, 3 month plan, compounded) puts Budget Fit at a below-par 55 — above the budget tiers.
Limited or undisclosed state coverage can slow your start, for a below-par 67 on Speed to Start.
Ryze Rx sticks to compounded injectables, for a below-par 66 on Formulary Match.
Support lands at a below-par 68 — lighter, meds-first support.
Flexibility scores a below-par 41 — fewer levers to flex your plan.
Thinner public disclosure than the top of the ranking keeps Transparency at a below-par 72.
Pricing in context
How Ryze Rx's monthly price sits against the category median and the cheapest provider we track.
What we like
- Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
- Physician consultation, ongoing clinical support and discreet shipping included with each prescription
- Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)
- Free shipping, 24hr prescription turnaround, FSA/HSA eligible; care advertised in all 50 states
The caveats
- Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
- Pharmacy partners not named - only 'US-licensed compounding pharmacies'
- Homepage advertises GLP-1s 'from $149/mo' but the catalog lists $199/mo
- On-site '4.9/5, 2,400+ reviews' is self-reported, not an independently verified rating
Who it's for — and who should skip it
Ryze Rx is for people who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.
Skip it if that doesn't sound like you. A closer fit may be MEDGm (Match Score 60) — or take the quiz to see where Ryze Rx lands for your priorities.
How it compares to CoreAge Rx & the closest scorer
Ryze Rx against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.
| How it compares | Ryze Rxthis provider | CoreAge Rxour #1 | LevelsRxclosest scorer |
|---|---|---|---|
| Sema price | $199/mo (starting dose, 3 month plan, compounded) | $99/mo at every dose | $253/mo |
| Coverage | Coverage not published | All 50 states | Coverage not published |
| Formulary | Injectable | Injectable | Injectable + oral |
| Match Score | 61 · C | 91 · A− | 61 · C |
Ryze Rx, answered
Is Ryze Rx legit?
Ryze Rx is a real, operating GLP-1 telehealth program. LegitScript certification is the third-party check worth asking for — look for the seal on their site and confirm your prescriber is US-licensed at intake. Like most programs here it dispenses compounded GLP-1s, which are made by a licensed pharmacy but aren't FDA-approved.
How much does Ryze Rx cost?
Ryze Rx lists compounded semaglutide from $199/mo (starting dose, 3 month plan, compounded) and tirzepatide from $166/mo — right at our category median. These are the provider's public figures at our last review (August 2026); confirm on their site, since some teaser tiers step up after month one.
Does Ryze Rx ship to my state?
Ryze Rx doesn't publish a full state list, so confirm your state is covered during intake before you pay.
Ryze Rx vs MEDGm — which should I pick?
They score within a few points of each other: Ryze Rx at 61/100 and MEDGm at 60/100, so neither wins on the headline number. Ryze Rx is the better fit for people who want compounded GLP-1s plus a broad TRT and peptide menu on one platform. MEDGm suits people who want four named pharmacies and a fifty-state footprint, and who will click the coupon off before deciding what the program costs. Run the quiz and the weighting shifts to whichever of those matters more to you.
Pricing & state data last verified August 2026 from Ryze Rx's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Ryze Rx's site. Not medical advice; see our disclosure.
Semaglutide here is $199/mo (starting dose, 3 month plan, compounded) — almost exactly our category median of $199. Tirzepatide is $166/mo. It scores highest on what it is willing to publish up front. Best suited to people who want compounded GLP-1s plus a broad TRT and peptide menu on one platform. If that is not you, MEDGm is the closest thing to it here.
Compare with other providers
Our next-best picks in default ranking order, then the 24 programs that sit nearest Ryze Rx here.
- #1Match91/ 100CoreAge RxThe best all-around match: nationwide access, both molecules at one flat, no-surprise price, and an easy exit.91/100
- #2Match84/ 100Strut HealthThe only program here carrying both LegitScript and ACHC accreditation, with an oral lozenge route on both molecules at the cheapest entry in this ranking.84/100
- #3Match83/ 100EdenA polished, high-disclosure compounded program with strong nationwide coverage and hands-on support.83/100
- #4Match85/ 100RoA heavyweight telehealth brand with brand-name access and a polished experience — but opaque compounded pricing.85/100
- #5Match85/ 100No BS RXThe highest Transparency score here, and it is not close: twenty-four prices on one public page and four dispensing pharmacies named with street addresses.85/100
Compare 24 nearby providersHide them
| Provider | Tirzepatide price | Coverage | Alternatives | Go | ||
|---|---|---|---|---|---|---|
| Next Vial#328 | 61 | $199/mo | Not disclosed | 49 states | Alternatives | Visit |
| Novi#329 | 61 | $149/mo | $405/mo | Coverage not published | Alternatives | Visit |
| Rewinding RX#330 | 61 | $141/mo | $192/mo | All 50 states | Alternatives | Visit |
| HealthHub#331 | 61 | $100/mo | $202/mo | Coverage not published | Alternatives | Visit |
| Solaya MD#332 | 61 | Not disclosed | Not disclosed | All 50 states | Alternatives | Visit |
| Lttl#333 | 58 | $216/mo | $303/mo | Coverage not published | Alternatives | Visit |
| Fifty 410#334 FDA issued Aspen Aesthetics dba Fifty 410 a warning letter in February 2026. See FDA's warning-letter database. | 60 | $199/mo | $133/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Ivim Health#335 | 60 | $268/mo | $355/mo | Coverage not published | Alternatives | Visit |
| TeleHealth Med#336 | 60 | $263/mo | Not disclosed | Coverage not published | Alternatives | Visit |
| June Health#337 | 60 | $283/mo | $202/mo | Coverage not published | Alternatives | Visit |
| Neo Soma Healthcare#338 | 60 | $216/mo | $239/mo | Coverage not published | Alternatives | Visit |
| Pomegranate Health#339 | 60 | $129/mo | $149/mo (Starter plan, dose not published, compounded) | Coverage not published | Alternatives | Visit |
| Premium Health#340 FDA issued Premium Health Management Inc. dba Premium Health a warning letter in February 2026. See FDA's warning-letter database. | 60 | $275/mo (all doses, compounded) | $445/mo (all doses, compounded) | Coverage not published | Alternatives | Visit |
| WeightCare#341 FDA issued Weightless Medical LLC dba WeightCare a warning letter in February 2026. See FDA's warning-letter database. | 60 | $399/mo | $499/mo (15 mg dose, compounded) | Coverage not published | Alternatives | Visit |
| 9amHealth#342 | 60 | $149/mo (plus a separate fee, brand-name) | Not disclosed | Coverage not published | Alternatives | Visit |
| Aurelius Health Group#343 | 60 | Not disclosed | $199/mo (microdose tier, compounded) | Coverage not published | Alternatives | Visit |
| CVS MinuteClinic#344 | 60 | Not disclosed | Not disclosed | Coverage not published | Alternatives | Visit |
| Genesis Health#345 FDA issued Genesis Health International Inc. dba Genesis a warning letter in February 2026. See FDA's warning-letter database. | 60 | $178/mo | $228/mo | Coverage not published | Alternatives | Visit |
| PrideRx#346 | 60 | $149/mo (starting dose, plus a separate fee, brand-name) | $299/mo (2.5 mg dose, plus a separate fee, brand-name) | Coverage not published | Alternatives | Visit |
| Oxford's Medical Weight Loss (The Calibrate Clinic)#347 | 60 | $218/mo | $334/mo | 2 states | Alternatives | Visit |
| Vitalex Health#348 | 60 | $199/mo (starting dose, compounded) | $199/mo (starting dose, compounded) | Coverage not published | Alternatives | Visit |
| Harmony Wellness Clinic#349 | 60 | $203/mo | $254/mo | 36 states | Alternatives | Visit |
| Lumora#350 | 60 | $249/mo | $330/mo | Coverage not published | Alternatives | Visit |
| Obu Health#351 | 60 | $193/mo | $242/mo | Coverage not published | Alternatives | Visit |
Ryze Rx is ranked on our best semaglutide providers, best tirzepatide providers and best GLP-1 programs boards, scored on the same six factors as every other provider there.