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Match Score 74 · Grade C

Blis MD review: price, pros & cons

By MatchScript EditorialUpdated

A Florida-based virtual clinic selling compounded semaglutide and tirzepatide by the one-month vial, from $109 and $159 at the starting dose with a published price for every step up, plus an oral semaglutide tablet, with no doctor's fee and no subscription.

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Blis MD is a small Florida-based virtual clinic that sells compounded semaglutide and tirzepatide one vial at a time.

Semaglutide
$109/mo (starting dose)
Tirzepatide
$159/mo (starting dose)
Coverage
29 states: AZ, CA, CO, CT, FL, GA, IL, IN, KY, MA, MD, MI, MO, NC, ND, NV, NY, OH, OK, OR, PA, SC, SD, TN, TX, UT, VA, WA and WY
Brand-name
Not listed
Oral option
Yes
Verification
Not independently listed

Best for: Readers in its 29 states who want to see the exact price of every dose before they start, pay only when they reorder, and have the option of a free consultation first.

MatchScript's take: Clear per-dose pricing from $109 and no subscription, though the bill climbs as your dose does and the pharmacy is not named.

The factor breakdown

Blis MD on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.

Budget Fit70/100

Semaglutide starts at $109 for a month at the starting dose, in the $101–125 band, held at 70 because the price rises to $189 at higher doses.

Speed to Start72/100

A five-minute online intake, approval and shipping in 24 to 48 hours for most patients, and 29 named states; a consultation is optional.

Formulary Match83/100

Compounded semaglutide and tirzepatide injections, an oral semaglutide tablet, and peptides such as sermorelin, NAD+ and GHK-Cu; no brand-name medication.

Support Level70/100

In-account messaging with a 24-hour reply, provider check-ins and nutrition guidance; clinicians are not named.

Flexibility80/100

Every order is a one-time purchase with no subscription, so you reorder only when you choose.

Transparency72/100

Every dose price and the state list are published, but the pharmacy is not named and one page shows outdated prices.

Pricing in context

How Blis MD's monthly price sits against the category median and the cheapest provider we track.

Monthly priceSemaglutideTirzepatide
Blis MDthis providerVisit $109/mo (starting dose)−$81 vs median$159/mo (starting dose)−$100 vs median
Category median240 tracked$190/mo$259/mo
Cheapest trackedMondaeVisit $87/mo$126/mo

For a fair comparison, check the full cost of semaglutide or tirzepatide, including care fees, dose changes and the amount due at each renewal.

What we found on their site

Read on Blis MD's own website in October 2026. Quoted text is theirs.

  • The plan list starts at "1 mg / 0.5mg /ml (1ml vial) (1 mth supply - .25 mg p/wk)" for $109.00 and ends at the 10 mg vial "(1 mth supply - 2.5 mg p/wk)" for $189.00.
  • The product description says "No Doctor's fees or subscription fees!" and "Each bottle is a 1-month supply."
  • Its FAQ answers the state question with "We are currently serving the following states: AZ, CA, CO, CT, FL, GA, IL, IN, KY, MA, MD, MI, MO, NC, ND, NV, NY, OH, OK, OR, PA, SC, SD, TN, TX, UT, VA, WA, WY."

What we like

  • Every dose has a published one-month price: semaglutide runs from $109 to $189 and tirzepatide from $159 to $270
  • No doctor's fee and no subscription: each vial is a one-time purchase, and the card is charged only if you are approved
  • An oral semaglutide tablet with vitamin B6 is sold alongside the injections, from $159
  • Three-month kits covering the next three dose steps cut the cost by $49 to $201
  • Patients can message their practitioner from their account, with a reply promised within 24 hours, and free shipping and HSA/FSA payment are offered

The caveats

  • Prices rise with your dose: semaglutide reaches $189 a month at 2.5 mg a week and tirzepatide $270 at 15 mg a week
  • Its weight-loss page still quotes older starting prices of $139 for semaglutide and $199 for tirzepatide, which do not match the product pages
  • The compounding pharmacy is not named, and the medical director is described but not named
  • Only 29 states are served
  • The tirzepatide page's own example (a 10 mg order arriving as a 40 mg vial) does not match its vial list, so confirm what you are buying before you pay

Blis MD · semaglutide $109/mo (starting dose) · tirzepatide $159/mo (starting dose)Check the current price and eligibility on their site.

Visit Blis MD

Who it's for — and who should skip it

Blis MD is for readers in its 29 states who want to see the exact price of every dose before they start, pay only when they reorder, and have the option of a free consultation first.

Skip it if that doesn't sound like you. A closer fit may be Oak (Match Score 74) — or take the quiz to see where Blis MD lands for your priorities.

See every alternative to Blis MD.

Before you choose care

What semaglutide costs. Compare medication costs, ongoing fees and prepaid plans before choosing care.

What tirzepatide costs. See how dose, medication type and billing terms affect the total price.

Oral GLP-1s vs. injections. Understand the differences between approved oral medicines, compounded forms and injections.

Compounded vs. brand-name GLP-1s. Learn how approval, evidence and pharmacy oversight differ between these options.

How it compares to CoreAge Rx & the closest scorer

Blis MD against CoreAge Rx and the provider that scores closest to it. Green marks the row leader.

How it comparesBlis MDthis providerCoreAge RxfeaturedOakclosest scorer
Sema price$109/mo (starting dose)$99/mo at every dose$190/mo
Coverage29 states: AZ, CA, CO, CT, FL, GA, IL, IN, KY, MA, MD, MI, MO, NC, ND, NV, NY, OH, OK, OR, PA, SC, SD, TN, TX, UT, VA, WA and WYU.S. only — restrictions vary by state and therapy, list not publishedAll 50 states
FormularyInjectable + oralInjectableInjectable + oral + brand
Match Score74 · C91 · A−74 · C

Blis MD, answered

Is Blis MD legit?

Blis MD is a real, operating GLP-1 telehealth program. LegitScript certification is the third-party check worth asking for — look for the seal on their site and confirm your prescriber is US-licensed at intake. Like most programs here it dispenses compounded GLP-1s, which are made by a licensed pharmacy but aren't FDA-approved.

How much does Blis MD cost?

Blis MD lists compounded semaglutide from $109/mo (starting dose) and tirzepatide from $159/mo (starting dose) — below our category median of $190/mo. These are the provider's public figures at our last review; confirm on their site, since some teaser tiers step up after month one.

Does Blis MD ship to my state?

Blis MD operates in a limited set of states (29 states: AZ, CA, CO, CT, FL, GA, IL, IN, KY, MA, MD, MI, MO, NC, ND, NV, NY, OH, OK, OR, PA, SC, SD, TN, TX, UT, VA, WA and WY). If yours isn't on that list, you'll need a nationwide provider instead.

Blis MD vs Oak — which should I pick?

They score within a few points of each other: Blis MD at 74/100 and Oak at 74/100, so neither wins on the headline number. Blis MD is the better fit for readers in its 29 states who want to see the exact price of every dose before they start, pay only when they reorder, and have the option of a free consultation first. Oak suits people who want compounded and brand-name options under one roof and a quick, video-free start, and who will confirm the exact price for their medication at checkout. Run the quiz and the weighting shifts to whichever of those matters more to you.

Pricing & state data come from Blis MD's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Blis MD's site. Not medical advice; see our disclosure.

Verdict · Grade C · 74/100

Blis MD is a small Florida-based virtual clinic that sells compounded semaglutide and tirzepatide one vial at a time. Each vial is a month's supply at a set dose, and every step is priced on the page: semaglutide from $109 at the starting dose to $189 at 2.5 mg a week, tirzepatide from $159 to $270. There is no doctor's fee and no subscription, you are charged only if approved, and three-month kits lower the cost if you plan ahead. An oral semaglutide tablet is also offered. The drawbacks: the bill rises as your dose increases, an older page still shows different starting prices, the pharmacy and medical director are not named, and only 29 states are served. Bottom line: a good fit if you value seeing every price up front and paying as you go, as long as you budget for the higher doses.

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Blis MD appears on our best semaglutide providers, best tirzepatide providers, best GLP-1 programs and best oral GLP-1 providers boards, scored on the same six factors as every other provider there.

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