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Ranked #141 of 537 · Grade C

Trillium Meds review

Trillium Meds is a small, owner-operated telehealth platform based in Portland, OR that connects patients with independent licensed providers and FDA-registered compounding pharmacies for compounded…

Visit Trillium Meds Or see your best match We may earn a commission if you start care through some of these links, at no extra cost to you. What we write about a provider is the same either way, providers we have a commercial relationship with are listed first on most boards, and every Match Score is computed from the six published factor sub-scores regardless. See our disclosure.

Semaglutide here is $159/mo — $40 below our category median of $199.

Semaglutide
$159/mo
Tirzepatide
$249/mo
Coverage
All 50 states
Brand-name
Compounded only
Oral option
Injectable only
Verification
LegitScript-certified

Best for: People who want legitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo).

MatchScript's take: Our #141 pick of 537 — priced at or below the category median.

The factor breakdown

Trillium Meds on the six Match Score factors — the same sub-scores the quiz reweights to your priorities. See the methodology.

Budget Fit62/100

Semaglutide from $159/mo puts Budget Fit at a below-par 62 — above the budget tiers.

Speed to Start97/100

Confirmed all-50-state access means it can usually prescribe within days, for an exceptional 97 on Speed to Start.

Formulary Match66/100

Trillium Meds sticks to compounded injectables, for a below-par 66 on Formulary Match.

Support Level79/100

Support lands at a middling 79 — lighter, meds-first support.

Flexibility20/100

Flexibility scores a below-par 20 — fewer levers to flex your plan.

Transparency90/100

LegitScript certification and clear public disclosures put Transparency at a strong 90.

Pricing in context

How Trillium Meds's monthly price sits against the category median and the cheapest provider we track.

Monthly priceSemaglutideTirzepatide
Trillium Medsthis providerVisit $159/mo$40 vs median$249/mo$25 vs median
Category median430 tracked$199/mo$274/mo
Cheapest trackedMondaeVisit $87 per 28 days (13 charges a year)$126 per 28 days (13 charges a year)

What we like

  • LegitScript certified with an active seal; serves all 50 states plus Puerto Rico with no geographic restrictions
  • All-inclusive pricing covers medication, provider consultation, and shipping with no hidden fees or add-ons
  • Two pharmacy options (BPI Labs with B6, ProRx) and three plan structures: 1-month, 3-month fixed, or 3-month titrated
  • Small owner-operated; founder personally handles customer support outside business hours for direct, responsive service
  • Klarna and Affirm financing available; pause anytime with no long-term commitment required

The caveats

  • No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
  • Small single-operator platform may limit capacity and support consistency as patient volume grows
  • Compounded medications are not FDA-approved; newer platform with limited long-term public track record
  • Tirzepatide from $199/mo (3-mo plan) is mid-market; sema from $119/mo competitive but not lowest available
  • No live video consult disclosed; async intake-form-based provider review by external licensed provider network

Who it's for — and who should skip it

Trillium Meds is for people who want legitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo).

Skip it if that doesn't sound like you. A closer fit may be RxSpan MD (Match Score 70) — or take the quiz to see where Trillium Meds lands for your priorities.

See every alternative to Trillium Meds.

How it compares to CoreAge Rx & the closest scorer

Trillium Meds against our #1 overall pick and the provider that scores closest to it. Green marks the row leader.

How it comparesTrillium Medsthis providerCoreAge Rxour #1Kin Medsclosest scorer
Sema price$159/mo$99/mo at every dose$202/mo
CoverageAll 50 statesAll 50 statesCoverage not published
FormularyInjectableInjectableInjectable + oral + brand
Match Score69 · C91 · A−69 · C

Trillium Meds, answered

Is Trillium Meds legit?

Yes — Trillium Meds is LegitScript-certified, a third-party check that a telehealth pharmacy operates within the rules. Like most programs here it dispenses compounded GLP-1s, which are made by a licensed pharmacy but aren't FDA-approved; confirm your prescriber is US-licensed at intake.

How much does Trillium Meds cost?

Trillium Meds lists compounded semaglutide from $159/mo and tirzepatide from $249/mo — below our category median of $199/mo. These are the provider's public figures at our last review (August 2026); confirm on their site, since some teaser tiers step up after month one.

Does Trillium Meds ship to my state?

Yes — Trillium Meds reports availability in all 50 states, so most people can start within days.

Trillium Meds vs RxSpan MD — which should I pick?

They score within a few points of each other: Trillium Meds at 69/100 and RxSpan MD at 70/100, so neither wins on the headline number. Trillium Meds is the better fit for people who want legitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo). RxSpan MD suits readers who want the pharmacy and the prescriber named up front and both a needle-free and a brand-name lane on the same account, and who will switch the plan selector back to Monthly themselves. Run the quiz and the weighting shifts to whichever of those matters more to you.

Pricing & state data last verified August 2026 from Trillium Meds's public site and our master provider matrix. The Match Score and its sub-scores are our editorial judgment per the methodology. Commercial facts only — prices change, so confirm on Trillium Meds's site. Not medical advice; see our disclosure.

Verdict · Grade C · 69/100

Semaglutide here is $159/mo — $40 below our category median of $199. Tirzepatide is $249/mo. It scores highest on how quickly you can start. Best suited to people who want legitScript-certified compounded GLP-1 telehealth, all 50 states + PR; sema $119/mo, tirz $199/mo (3-mo). If that is not you, RxSpan MD is the closest thing to it here.

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Trillium Meds is ranked on our best semaglutide providers, best tirzepatide providers and best GLP-1 programs boards, scored on the same six factors as every other provider there.

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